Advances and opportunities in nanoparticle‐and nanomaterial‐based vaccines against bacterial infections

LCW Lin, S Chattopadhyay, JC Lin… - Advanced healthcare …, 2018 - Wiley Online Library
As the dawn of the postantibiotic era we approach, antibacterial vaccines are becoming
increasingly important for managing bacterial infection and reducing the need for antibiotics …

Chlamydia trachomatis: Protective Adaptive Responses and Prospects for a Vaccine

TB Poston, T Darville - Biology of Chlamydia, 2018 - Springer
Chlamydia trachomatis is the most common cause of sexually transmitted bacterial infection
globally. These infections translate to a significant public health burden, particularly …

T cell-independent gamma interferon and B cells cooperate to prevent mortality associated with disseminated Chlamydia muridarum genital tract infection

TB Poston, CM O'Connell, J Girardi… - Infection and …, 2018 - Am Soc Microbiol
ABSTRACT CD4 T cells and antibody are required for optimal acquired immunity to
Chlamydia muridarum genital tract infection, and T cell-mediated gamma interferon (IFN-γ) …

The p110δ isoforme of phosphatidylinositol 3-kinase plays an important role in host defense against chlamydial lung infection through influencing CD4+ T-cell …

S Qiao, N Zheng, L Sun, G Pang, S Wang… - Pathogens and …, 2018 - academic.oup.com
PI3Ks display integrant significance in T-cell development and differentiation, which is
related to host defense against infections. Here, we investigated the role of p110δ isoform of …

Characterisation of lymphocytes and cytokines in healthy and diseased koalas (Phascolarctos cinereus) using cell-type-specific monoclonal antibodies

C Mangar - 2018 - eprints.qut.edu.au
This thesis is a step forward in developing scientific tools and methods to study the koala
(Phascolarctos cinereus) immune system in health and disease. Koala numbers are …

T-cell Dependent and independent mechanisms of chlamydial eradication and control

T Poston - 2018 - d-scholarship.pitt.edu
Evidence suggests that Th1 cells and antibody are the primary mediators of chlamydial
protection. However, the impact of Th1 polyfunctionality and T-cell independent antibody on …

Identification of Cytokine Profiles Associated with Endometrial Chlamydia Infection

DAE Lee - 2018 - cdr.lib.unc.edu
Chlamydia trachomatis (CT) infection can lead to reproductive tract morbidities when it
ascends to the upper genital tract of women, and repeated infections worsen disease …

[引用][C] Correlates of protection

SA Plotkin, P Gilbert - Plotkin's Vaccines, 2018 - Elsevier