Epithelial cell dysfunction is postulated as an important component in the pathogenesis of
idiopathic pulmonary fibrosis (IPF). Mutations in the surfactant protein C (SP-C) gene …

Abstract Surfactant protein C (SP-C) deficiency causes diffuse lung disease with variable
prognosis and severity that usually presents in infancy. We present the case of a patient with …

Background To determine population-based prevalence and disease contribution of
phosphatidylcholine synthetic pathway-associated gene variants in a native southern …

Diffuse lung disease in infancy includes a wide range of very rare and peculiar pulmonary
conditions usually not seen in older children, in whom diffuse lung disease has much …

Pulmonary pathology includes a large spectrum of both neoplastic and nonneoplastic
diseases that affect the lung. Many of these diseases are the result of the unusual …

Pulmonary fibrosis is a diverse group of disorders with various etiologies and characterized
by varying patterns of lung inflammation and fibrosis. To date, familial aggregation has been …