Achievements in robotic automation of solvent extraction and related approaches for bioanalysis of pharmaceuticals

M Alexovič, Y Dotsikas, P Bober, J Sabo - Journal of Chromatography B, 2018 - Elsevier
Currently, the growing demand on quick, easy and ecological sample pretreatment methods
is unquestionable. Such challenge involves also approaches focusing on the analysis of …

Life cycle management of analytical methods

MK Parr, AH Schmidt - Journal of pharmaceutical and biomedical analysis, 2018 - Elsevier
In modern process management, the life cycle concept gains more and more importance. It
focusses on the total costs of the process from invest to operation and finally retirement. Also …

Molecularly imprinted polymers as extracting media for the chromatographic determination of antibiotics in milk

D Bitas, V Samanidou - Molecules, 2018 - mdpi.com
Milk-producing animals are typically kept stationary in overcrowded large-scale farms and in
most cases under unsanitary conditions, which promotes the development of infections. In …

Fast and easy extraction of antidepressants from whole blood using ionic liquids as extraction solvent

M De Boeck, L Dubrulle, W Dehaen, J Tytgat… - Talanta, 2018 - Elsevier
This study aims to prove that ionic liquids (ILs) can be used as extraction solvents in a liquid-
liquid microextraction, coupled to LC-MS/MS, for the quantification of a large group of …

An automated continuous homogeneous microextraction for the determination of selenium and arsenic by hydride generation atomic fluorescence spectrometry

A Shishov, M Wieczorek, P Kościelniak… - Talanta, 2018 - Elsevier
An automated continuous homogeneous microextraction approach based on a flow system
has been developed and coupled with a hydride generation atomic fluorescence …

Sample preparation for large‐scale bioanalytical studies based on liquid chromatographic techniques

A Medvedovici, E Bacalum… - Biomedical …, 2018 - Wiley Online Library
Quality of the analytical data obtained for large‐scale and long term bioanalytical studies
based on liquid chromatography depends on a number of experimental factors including the …

Green analytical chemistry and quality by design: A combined approach towards robust and sustainable modern analysis

S Saroj, P Shah, V Jairaj… - Current Analytical …, 2018 - ingentaconnect.com
Background: Since its origin, Green Chemistry has been focusing on the need for
eliminating or minimizing the harmful effects of various organic solvents used, on health as …

An improved and miniaturized analytical strategy based on μ-QuEChERS for isolation of polyphenols. A powerful approach for quality control of baby foods

N Casado, R Perestrelo, CL Silva, I Sierra… - Microchemical …, 2018 - Elsevier
An improved and miniaturized quick, easy, cheap, effective, rugged and safe (μ-QuEChERS)
strategy combined with ultra-high pressure liquid chromatography coupled to a photodiode …

Ultrasound-assisted dispersive liquid-liquid microextraction followed by gas chromatography–mass spectrometry for determination of parabens in human breast tumor …

X Shen, J Liang, L Zheng, H Wang, Z Wang, Q Ji… - … of Chromatography B, 2018 - Elsevier
An efficient method for the determination of eight parabens in human breast tumor (n= 102)
and peripheral adipose tissue samples (n= 87) was successfully developed. After a …

Preparation and application of a restricted access material with hybrid poly (glycerol mono-methacrylate) and cross-linked bovine serum albumin as hydrophilic out …

W Huang, P Wang, P Jiang, X Dong, S Lin - Journal of Chromatography A, 2018 - Elsevier
A novel restricted access material (RAM) was prepared through combination of hydrophilic
polymer poly (glycerol mono-methacrylate) and cross-linking bovine serum albumin (BSA) …