Animal models have been developed to study the complex cellular and biochemical
processes of wound repair and to evaluate the efficacy and safety of potential therapeutic …

Recovery from systemic or local bacterial infections can be lengthy and costly, with the
clinical challenges being further complicated when bacteria acquire resistance to current …

Introduction Staphylococcus aureus including methicillin-resistant S. aureus (MRSA) has the
propensity to form biofilms, and causes significant mortality and morbidity in the patients with …

Infected tissues in the feet of people with diabetes in the form of a diabetic foot ulcer (DFU)
present a complex pathology for clinicians to manage. This is partly attributed to the multi …

Wound healing is a highly complex process of tissue repair that relies on the synergistic
effect of a number of different cells, cytokines, enzymes, and growth factors. A deregulation …

Biofilms are responsible for stimulating and maintaining wound inflammation, increasing
infection risk and delaying wound closure. Appropriate biofilm management is required to …

Objective: Removal of slough and other devitalised tissue is an important step in biofilm-
based wound care (BBWC) and wound bed preparation. Debridement is key to …

Bacterial biofilms impair healing in 60% of chronic skin wounds. Various animal models
(mice, rats, rabbits, and pigs) have been developed to replicate biofilm infected wounds in …

The aim of this study was to evaluate the virulence of Staphylococcus aureus in a controlled
animal study using the standard sterile gauze and negative pressure wound therapy …

The addition of antimicrobial agents to wound dressings is used to reduce the risk of wound
infection, and help manage local wound infections, thereby facilitating wound progression …