Clostridium perfringens, a rapid-growing pathogen known to secrete an arsenal of> 20
virulent toxins, has been associated with intestinal diseases in both animals and humans …

Background Whole genome sequence (WGS)-based strain typing finds increasing use in the
epidemiologic analysis of bacterial pathogens in both public health as well as more …

Clostridium difficile is a leading cause of antibiotic-associated diarrhea worldwide. The
diagnosis of C. difficile infection (CDI) requires both clinical manifestations and a positive …

Abstract Background Rates of Clostridium difficile infection vary widely across Europe, as do
prevalent ribotypes. The extent of Europe-wide diversity within each ribotype, however, is …

Objectives The increased incidence and severity of Clostridium difficile infection (CDI) are
thought to result partly from the emergence of the hypervirulent BI/NAP1/027 strain. Limited …

Abstract Background Traditionally, Clostridium difficile has been considered a typical
healthcare-associated pathogen—that is, one transmitted within healthcare facilities and …

A substantial proportion of Clostridium difficile infection (CDI) cases recur after completion of
antibiotic therapy, and antibiotic cure rates diminish with each recurrence of CDI. Fecal …

In 2015, a marked increase in vancomycin-resistant Enterococcus faecium (VREfm) isolation
was detected at the Royal Hobart Hospital, Australia. The primary objective of this work was …

Clostridium difficile is a major cause of hospital-associated diarrhoea, and in severe cases
leads to pseudomembranous colitis and toxic megacolon. The frequency of C. difficile …

Abstract Background Although pediatric Clostridium difficile infections (CDIs) are increasing,
C. difficile transmission patterns among children are poorly understood. Methods We …