Pathophysiology of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

V Manne, P Handa, KV Kowdley - Clinics in liver disease, 2018 - liver.theclinics.com
The pathophysiology of NAFL and NASH is complex and numerous intermediaries are
involved. Each year brings new and exciting developments as pieces of the …

Quantitative elastography methods in liver disease: current evidence and future directions

P Kennedy, M Wagner, L Castéra, CW Hong… - Radiology, 2018 - pubs.rsna.org
Chronic liver diseases often result in the development of liver fibrosis and ultimately,
cirrhosis. Treatment strategies and prognosis differ greatly depending on the severity of liver …

Principles of ultrasound elastography

A Ozturk, JR Grajo, M Dhyani, BW Anthony… - Abdominal …, 2018 - Springer
Tissue stiffness has long been known to be a biomarker of tissue pathology. Ultrasound
elastography measures tissue mechanical properties by monitoring the response of tissue to …

Diagnosis and evaluation of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis, including noninvasive biomarkers and transient elastography

E Tsai, TP Lee - Clinics in liver disease, 2018 - liver.theclinics.com
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver tests
in industrial countries. It encompasses the spectrum of liver damage from simple steatosis to …

Non-invasive diagnosis of liver fibrosis in patients with alcohol-related liver disease by transient elastography: an individual patient data meta-analysis

E Nguyen-Khac, M Thiele, C Voican… - The Lancet …, 2018 - thelancet.com
Background The value of transient elastography for the non-invasive diagnosis of alcohol-
related liver fibrosis is subject to debate. We did an individual patient data (IPD) meta …

[PDF][PDF] Increase in liver stiffness after transjugular intrahepatic portosystemic shunt is associated with inflammation and predicts mortality

C Jansen, P Möller, C Meyer, CC Kolbe, C Bogs… - …, 2018 - Wiley Online Library
Transjugular intrahepatic portosystemic shunt (TIPS) efficiently treats complications of portal
hypertension. Liver and spleen stiffness might predict clinically significant portal …

Targeted delivery of microRNA‐199a‐3p using self‐assembled dipeptide nanoparticles efficiently reduces hepatocellular carcinoma in mice

A Varshney, JJ Panda, AK Singh, N Yadav… - …, 2018 - Wiley Online Library
Hepatocellular carcinoma (HCC) is an aggressive tumor with limited systemic and
locoregional modalities of treatment. Although microRNA (miRNA) based therapies have …

Serial changes in liver stiffness and controlled attenuation parameter following direct‐acting antiviral therapy against hepatitis C virus genotype 1b

N Ogasawara, M Kobayashi, N Akuta… - Journal of medical …, 2018 - Wiley Online Library
Little information is available on the impact of direct‐acting antiviral (DAA) therapy on
changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation …

Hepatic steatosis assessment with ultrasound small-window entropy imaging

Z Zhou, DI Tai, YL Wan, JH Tseng, YR Lin, S Wu… - Ultrasound in medicine …, 2018 - Elsevier
Nonalcoholic fatty liver disease is a type of hepatic steatosis that is not only associated with
critical metabolic risk factors but can also result in advanced liver diseases. Ultrasound …

Changes in liver stiffness and steatosis among patients with hepatitis C virus infection who received direct-acting antiviral therapy and achieved sustained virological …

N Kobayashi, H Iijima, T Tada, T Kumada… - European journal of …, 2018 - journals.lww.com
Aim Whether direct-acting antiviral (DAA) therapy can reduce liver fibrosis and steatosis in
patients with chronic hepatitis C virus (HCV) infection remains unclear. We evaluated …