Macrophages and prognosis of oral squamous cell carcinoma: a systematic review

AM Alves, LF Diel, ML Lamers - Journal of Oral Pathology & …, 2018 - Wiley Online Library
Oral Squamous Cell Carcinoma (OSCC) presents a tumor microenvironment rich in
inflammatory cells. Depending on the stimulus, macrophages can polarize in M1 or M2 …

Transforming growth factor‑β signaling in head and neck squamous cell carcinoma: Insights into cellular responses

X Pang, YL Tang, XH Liang - Oncology letters, 2018 - spandidos-publications.com
Head and neck squamous cell carcinoma (HNSCC) arises in the oral cavity, salivary glands,
larynx, pharynx, nasal cavity and paranasal sinuses, and is characterized by high morbidity …

[HTML][HTML] Mining TCGA database for genes of prognostic value in glioblastoma microenvironment

DI Jia, S Li, D Li, H Xue, D Yang, Y Liu - Aging (Albany NY), 2018 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is one of the most deadly brain tumors. The convenient access to The
Cancer Genome Atlas (TCGA) database allows for large-scale global gene expression …

Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer

CM Carnielli, CCS Macedo, T De Rossi… - Nature …, 2018 - nature.com
Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological
and molecular characteristics limiting the standard tumor− node− metastasis prognosis …

Cancer-associated fibroblasts drive glycolysis in a targetable signaling loop implicated in head and neck squamous cell carcinoma progression

D Kumar, J New, V Vishwakarma, R Joshi, J Enders… - Cancer research, 2018 - AACR
Despite aggressive therapies, head and neck squamous cell carcinoma (HNSCC) is
associated with a less than 50% 5-year survival rate. Late-stage HNSCC frequently consists …

A subtype of cancer-associated fibroblasts with lower expression of alpha-smooth muscle actin suppresses stemness through BMP4 in oral carcinoma

AK Patel, K Vipparthi, V Thatikonda, I Arun… - Oncogenesis, 2018 - nature.com
Cancer-associated fibroblasts (CAFs) demonstrate the characteristics of myofibroblast
differentiation by often expressing the ultrastructure of alpha-smooth muscle actin (αSMA) …

Oral cancer: genetics and the role of precision medicine

CC Li, Z Shen, R Bavarian, F Yang… - Dental …, 2018 - dental.theclinics.com
Dent Clin N Am 62 (2018) 29–46 http://dx. doi. org/10.1016/j. cden. 2017.08. 002 dental.
theclinics. com 0011-8532/18/© 2017 Elsevier Inc. All rights reserved. diagnosed cancer …

Factors secreted by cancer-associated fibroblasts that sustain cancer stem properties in head and neck squamous carcinoma cells as potential therapeutic targets

S Álvarez-Teijeiro, C García-Inclán, MÁ Villaronga… - Cancers, 2018 - mdpi.com
This study investigates for the first time the crosstalk between stromal fibroblasts and cancer
stem cell (CSC) biology in head and neck squamous cell carcinomas (HNSCC), with the …

[HTML][HTML] The histologic risk model is a useful and inexpensive tool to assess risk of recurrence and death in stage I or II squamous cell carcinoma of tongue and floor of …

N Sinha, MH Rigby, ML McNeil, SM Taylor, JRB Trites… - Modern Pathology, 2018 - Elsevier
Surgery is the mainstay of treatment for low-stage (stage I/II, ie, T1N0/T2N0) squamous cell
carcinoma of oral cavity. However, a significant percentage of low-stage squamous cell …

Efficacy and safety of anti‐EGFR agents administered concurrently with standard therapies for patients with head and neck squamous cell carcinoma: a systematic …

Y Tian, J Lin, Y Tian, G Zhang, X Zeng… - … journal of cancer, 2018 - Wiley Online Library
Agents targeting epidermal growth factor receptor (EGFR) are used to treat head and neck
squamous cell carcinoma (HNSCC); however, their efficacy and safety is poorly understood …