Genetic basis for congenital heart disease: revisited: a scientific statement from the American Heart Association

ME Pierpont, M Brueckner, WK Chung, V Garg… - Circulation, 2018 - Am Heart Assoc
This review provides an updated summary of the state of our knowledge of the genetic
contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial …

Genetic origins of tetralogy of Fallot

A Morgenthau, WH Frishman - Cardiology in review, 2018 - journals.lww.com
Due to improved survival and clinical outcomes, congenital heart disease (CHD) is an area
of growing importance within the medical community. As these patients reach adulthood and …

2018 ESC guidelines for the management of cardiovascular diseases during pregnancy: the task force for the management of cardiovascular diseases during …

V Regitz-Zagrosek, JW Roos-Hesselink… - European heart …, 2018 - academic.oup.com
not override in any way whatsoever the individual responsibility of health professionals to
make appropriate and accurate decisions in consideration of each patient's health condition …

Familial co-occurrence of congenital heart defects follows distinct patterns

SG Ellesøe, CT Workman, P Bouvagnet… - European heart …, 2018 - academic.oup.com
Aims Congenital heart defects (CHD) affect almost 1% of all live born children and the
number of adults with CHD is increasing. In families where CHD has occurred previously …

Pregnancy in women with congenital heart disease

M Cauldwell, F Dos Santos, PJ Steer, L Swan… - BMJ, 2018 - bmj.com
One in 125 people is born with congenital heart disease. 1 For women with the condition,
pregnancy induced cardiovascular stress can cause complications such as arrhythmia, heart …

[HTML][HTML] Some isolated cardiac malformations can be related to laterality defects

P Versacci, F Pugnaloni, MC Digilio, C Putotto… - Journal of …, 2018 - mdpi.com
Human beings are characterized by a left–right asymmetric arrangement of their internal
organs, and the heart is the first organ to break symmetry in the developing embryo …

Impact of improved survival in congenital heart disease on incidence of disease

S Bregman, WH Frishman - Cardiology in Review, 2018 - journals.lww.com
Survival rates and life expectancies for patients with congenital heart disease (CHD) have
dramatically increased, and these patients are now reaching reproductive age. As they …

Genomics and epigenomics of congenital heart defects: expert review and lessons learned in Africa

NE Thomford, K Dzobo, NA Yao… - OMICS: A Journal of …, 2018 - liebertpub.com
Congenital heart defects (CHD) are structural malformations found at birth with a prevalence
of 1%. The clinical trajectory of CHD is highly variable and thus in need of robust diagnostics …

Maternal congenital heart disease in pregnancy

ME Foeller, TM Foeller… - Obstetrics and Gynecology …, 2018 - obgyn.theclinics.com
Maternal cardiac disease is present in 1% of the pregnant population, 1 most of which
originates from congenital heart disease. 2 Global advances in recognizing and surgically …

Outcomes of pregnancy after right ventricular outflow tract reconstruction with an allograft conduit

JLR Romeo, JJM Takkenberg… - Journal of the American …, 2018 - jacc.org
Background There is no published evidence on pregnancy after right ventricular outflow tract
(RVOT) reconstruction with an allograft. Objectives The aim of this study was to describe …