Childhood-onset schizophrenia: Insights from induced pluripotent stem cells
A Hoffmann, M Ziller, D Spengler - International Journal of Molecular …, 2018 - mdpi.com
Childhood-onset schizophrenia (COS) is a rare psychiatric disorder characterized by earlier
onset, more severe course, and poorer outcome relative to adult-onset schizophrenia (AOS) …
onset, more severe course, and poorer outcome relative to adult-onset schizophrenia (AOS) …
Pervasive genetic interactions modulate neurodevelopmental defects of the autism-associated 16p11.2 deletion in Drosophila melanogaster
As opposed to syndromic CNVs caused by single genes, extensive phenotypic
heterogeneity in variably-expressive CNVs complicates disease gene discovery and …
heterogeneity in variably-expressive CNVs complicates disease gene discovery and …
Loss of the Chr16p11.2 ASD candidate gene QPRT leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model
D Haslinger, R Waltes, A Yousaf, S Lindlar, I Schneider… - Molecular autism, 2018 - Springer
Background Altered neuronal development is discussed as the underlying pathogenic
mechanism of autism spectrum disorders (ASD). Copy number variations of 16p11. 2 have …
mechanism of autism spectrum disorders (ASD). Copy number variations of 16p11. 2 have …
Using human induced neural precursor cells to define early neurodevelopmental defects in syndromic and idiopathic autism
RJ Connacher, E DiCicco-Bloom… - Current Pharmacology …, 2018 - Springer
Abstract Purpose of Review Autism spectrum disorder (ASD) is characterized as a
developmental brain disorder with a complex and undefined etiology. While animal studies …
developmental brain disorder with a complex and undefined etiology. While animal studies …
The ASD-associated CNV 16p11. 2: Functional study of the candidate gene QPRT
D Haslinger - 2018 - publikationen.ub.uni-frankfurt.de
Bei Autismus-Spektrum-Störungen (ASS) handelt es sich um genetisch komplexe Störungen
mit hoher Erblichkeit. Als zugrundeliegender Pathomechanismus von ASS werden unter …
mit hoher Erblichkeit. Als zugrundeliegender Pathomechanismus von ASS werden unter …
[PDF][PDF] A Review of the Placenta and Trophoblast Induced Pluripotent Stem Cells in Autism Spectrum Disorder Research
S Jasani, G Tartaglia, PL Yeung, CW Lu - J Stem Cell Res Ther, 2018 - researchgate.net
Autism spectrum disorder (ASD) imparts a tremendous health burden with psychological,
social, and economic implications. The biology of ASD is complex involving genetic …
social, and economic implications. The biology of ASD is complex involving genetic …
[图书][B] In vitro modelling of Lesch-Nyhan Disease
L Crapper - 2018 - search.proquest.com
Abstract Lesch-Nyhan Disease (LND) is a rare neurodevelopmental disorder characterized
by metabolic symptoms including the accumulation of uric acid crystals in the urine …
by metabolic symptoms including the accumulation of uric acid crystals in the urine …