Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases
A Pommier, N Anaparthy, N Memos, ZL Kelley… - Science, 2018 - science.org
INTRODUCTION Pancreatic ductal adenocarcinoma (PDA) is the fourth most common
cause of death from cancer worldwide and has a 5-year survival rate of 6%. Patients who …
cause of death from cancer worldwide and has a 5-year survival rate of 6%. Patients who …
Targeting pancreatic cancer cell plasticity: The latest in therapeutics
JM Smigiel, N Parameswaran, MW Jackson - Cancers, 2018 - mdpi.com
Mortality remains alarmingly high for patients diagnosed with pancreatic ductal
adenocarcinoma (PDAC), with 93% succumbing to the disease within five years. The vast …
adenocarcinoma (PDAC), with 93% succumbing to the disease within five years. The vast …
The predictive value and role of stromal tumor-infiltrating lymphocytes in pancreatic ductal adenocarcinoma (PDAC)
T Lianyuan, X Dianrong, Y Chunhui… - Cancer biology & …, 2018 - Taylor & Francis
Recently, increasing evidence has indicated that the presence of tumor infiltrating immune
cells has shown predictive significance for many solid tumors. Present study was performed …
cells has shown predictive significance for many solid tumors. Present study was performed …
MicroRNA-1179 inhibits the proliferation, migration and invasion of human pancreatic cancer cells by targeting E2F5
C Lin, Z Hu, G Yuan, H Su, Y Zeng, Z Guo… - Chemico-biological …, 2018 - Elsevier
Pancreatic cancer is one of deadly cancers and is responsible for significant mortality and
morbidity across the globe. The unavailability of the efficient chemotheruptic drugs and the …
morbidity across the globe. The unavailability of the efficient chemotheruptic drugs and the …
Global incidence and mortality rates in pancreatic cancer and the association with the Human Development Index: decomposition approach
Objectives Pancreatic cancer has a lower morbidity yet higher case fatality rates (CFRs)
compared with other gastrointestinal cancers. The effects of socio-economic components on …
compared with other gastrointestinal cancers. The effects of socio-economic components on …
Current molecular and genetic aspects of pancreatic cancer, the role of metastasis associated proteins (MTA): a review
ET Pavlidis, TE Pavlidis - Journal of Investigative Surgery, 2018 - Taylor & Francis
Purpose/aim: To focus on current molecular and genetic aspects and MTA proteins, since
pancreatic cancer is a lethal malignant with poor prognosis. Early diagnosis is essential …
pancreatic cancer is a lethal malignant with poor prognosis. Early diagnosis is essential …
[HTML][HTML] Mahanimbine exerts anticancer effects on human pancreatic cancer cells by triggering cell cycle arrest, apoptosis, and modulation of AKT/mammalian target …
C Pei, Q He, S Liang, X Gong - Medical science monitor …, 2018 - ncbi.nlm.nih.gov
Background Pancreatic cancer causes tremendous mortality across the globe mainly due to
late diagnosis and unavailability of efficient chemotheruptic agents. In the current study the …
late diagnosis and unavailability of efficient chemotheruptic agents. In the current study the …
Aberrant expression of PDZ-binding kinase/T-LAK cell-originated protein kinase modulates the invasive ability of human pancreatic cancer cells via the stabilization of …
CP Hinzman, L Aljehane, JD Brown-Clay… - …, 2018 - academic.oup.com
High frequency of mortality in patients with pancreatic ductal adenocarcinoma (PDAC) is
vastly associated with the invasive and metastatic nature of these cancer cells. Little is …
vastly associated with the invasive and metastatic nature of these cancer cells. Little is …
Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway
L Chen, D Zhou, Z Liu, X Huang, Q Liu… - Oncology …, 2018 - spandidos-publications.com
Compared to single gemcitabine treatment, the combination of gemcitabine and erlotinib
has shown effective response in patients with locally advanced or metastatic pancreatic …
has shown effective response in patients with locally advanced or metastatic pancreatic …
[HTML][HTML] The relationship between human development index and its components with thyroid cancer incidence and mortality: using the decomposition approach
Background The link between age specific-rates of thyroid cancer (TC) and human
development index (HDI) and also its components can be a new direction for planning by …
development index (HDI) and also its components can be a new direction for planning by …