Circulating tumor cells (CTCs) exist in a microenvironment quite different from the solid
tumor tissue microenvironment. They are detached from matrix and exposed to the immune …

Blood is arguably the most important bodily fluid and its analysis provides crucial health
status information. A first routine measure to narrow down diagnosis in clinical practice is the …

Red blood cells (RBCs) are the most abundant cells in human blood. Remarkably RBCs
deform and bridge together to form aggregates under very low shear rates. The theory and …

Partitioning of red blood cells (RBCs) at vascular bifurcations has been studied over many
decades using in vivo, in vitro, and theoretical models. These studies have shown that RBCs …

Red blood cells flowing through capillaries assume a wide variety of different shapes owing
to their high deformability. Predicting the realized shapes is a complex field as they are …

The cerebral microvasculature consists of pial vascular networks, parenchymal descending
arterioles, ascending venules and parenchymal capillaries. This vascular …

ATP is a major player as a signaling molecule in blood microcirculation. It is released by red
blood cells (RBCs) when they are subjected to shear stresses large enough to induce a …

We computationally study the motion of an initially spherical capsule flowing through a
straight channel with an orthogonal lateral branch, using a three-dimensional immersed …

Nanomedicine, nanotargeting and nanotherapeutics have in the last few years faced several
difficulties in translating the promising results obtained in vitro to an in vivo scenario. The …

We present a theory to describe the time evolution of the red blood cell (RBC) and platelet
concentration distributions in pressure-driven flow through a straight channel. This model is …