[HTML][HTML] The age-related loss of skeletal muscle mass and function: Measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans

DJ Wilkinson, M Piasecki, PJ Atherton - Ageing research reviews, 2018 - Elsevier
Age-related loss of skeletal muscle mass and function, sarcopenia, is associated with
physical frailty and increased risk of morbidity (chronic diseases), in addition to all-cause …

Defining anabolic resistance: implications for delivery of clinical care nutrition

RW Morton, DA Traylor, PJM Weijs… - Current opinion in …, 2018 - journals.lww.com
Insofar as atrophic loss of skeletal muscle mass is concerned, anabolic resistance is a
principal determinant of age-induced losses and appears to be a contributor to critical illness …

[HTML][HTML] Muscle androgen receptor content but not systemic hormones is associated with resistance training-induced skeletal muscle hypertrophy in healthy, young …

RW Morton, K Sato, MPB Gallaugher… - Frontiers in …, 2018 - frontiersin.org
The factors that underpin heterogeneity in muscle hypertrophy following resistance exercise
training (RET) remain largely unknown. We examined circulating hormones, intramuscular …

[HTML][HTML] Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older …

DJ Wilkinson, SSI Bukhari, BE Phillips, MC Limb… - Clinical nutrition, 2018 - Elsevier
Background & aims Impaired anabolic responses to nutrition and exercise contribute to loss
of skeletal muscle mass with ageing (sarcopenia). Here, we tested responses of muscle …

[HTML][HTML] Potential roles of n-3 PUFAs during skeletal muscle growth and regeneration

B Tachtsis, D Camera, O Lacham-Kaplan - Nutrients, 2018 - mdpi.com
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), which are commonly found in fish oil
supplements, are known to possess anti-inflammatory properties and more recently alter …

Molecular regulation of exercise-induced muscle fiber hypertrophy

MM Bamman, BM Roberts… - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Skeletal muscle hypertrophy is a widely sought exercise adaptation to counteract the muscle
atrophy of aging and disease, or to improve athletic performance. While this desired muscle …

Pronounced energy restriction with elevated protein intake results in no change in proteolysis and reductions in skeletal muscle protein synthesis that are mitigated by …

AJ Hector, C McGlory, F Damas, N Mazara… - The FASEB …, 2018 - Wiley Online Library
Preservation of lean body mass (LBM) may be important during dietary energy restriction
(ER) and requires equal rates of muscle protein synthesis (MPS) and muscle protein …

Regional regulation of focal adhesion kinase after concentric and eccentric loading is related to remodelling of human skeletal muscle

MV Franchi, S Ruoss, P Valdivieso… - Acta …, 2018 - Wiley Online Library
Aims We assessed focal adhesion kinase (FAK) response to concentric (CON) vs eccentric
(ECC) resistance training (RT) at two vastus lateralis (VL) sites, and the relationships …

[HTML][HTML] Enhanced skeletal muscle ribosome biogenesis, yet attenuated mTORC1 and ribosome biogenesis-related signalling, following short-term concurrent versus …

JJ Fyfe, DJ Bishop, JD Bartlett, ED Hanson… - Scientific reports, 2018 - nature.com
Combining endurance training with resistance training (RT) may attenuate skeletal muscle
hypertrophic adaptation versus RT alone; however, the underlying mechanisms are unclear …

Fast digestive proteins and sarcopenia of aging

Y Boirie, C Guillet - Current Opinion in Clinical Nutrition & …, 2018 - journals.lww.com
Using fast digestive proteins is of major interest to overcome 'anabolic resistance'of aging for
limiting sarcopenia. Fast proteins' action on muscle anabolism may be stimulated by other …