Precision medicine for urothelial bladder cancer: update on tumour genomics and immunotherapy

KM Felsenstein, D Theodorescu - Nature Reviews Urology, 2018 - nature.com
Effective management of advanced urothelial bladder cancer is challenging. New
discoveries that improve our understanding of molecular bladder cancer subtypes have …

Patterns and predictors of recurrence after open radical cystectomy for bladder cancer: a comprehensive review of the literature

A Mari, R Campi, R Tellini, G Gandaglia… - World journal of …, 2018 - Springer
Purpose To review the currently available literature reporting the patterns of recurrence and
their predictive factors after open radical cystectomy (RC) for bladder cancer. Methods A …

Perioperative outcomes and complications of intracorporeal vs extracorporeal urinary diversion after robot-assisted radical cystectomy for bladder cancer: a real-life …

L Lenfant, G Verhoest, R Campi, J Parra… - World journal of …, 2018 - Springer
Purpose To compare perioperative outcomes and complications of extracorporeal (ECUD)
vs intracorporeal urinary diversion (ICUD) in patients after undergoing robot-assisted radical …

Perioperative chemotherapy for bladder cancer in the general population: Are practice patterns finally changing?

CM Booth, S Karim, K Brennan, DR Siemens… - … Oncology: Seminars and …, 2018 - Elsevier
Background Uptake of perioperative chemotherapy for muscle-invasive bladder cancer
(MIBC) has been historically poor. We describe contemporary use of neoadjuvant (NACT) …

Perioperative immunonutrition modulates inflammatory response after radical cystectomy: results of a pilot randomized controlled clinical trial

JM Hamilton-Reeves, A Stanley, MD Bechtel… - The Journal of …, 2018 - auajournals.org
Purpose: Poor preoperative nutritional status is associated with a higher complication rate
after radical cystectomy in patients with bladder cancer. Given the short interval between …

Neoadjuvant treatment for muscle-invasive bladder cancer: The past, the present, and the future

TJN Hermans, CS Voskuilen… - … Oncology: Seminars and …, 2018 - Elsevier
Background Approximately half of patients who undergo radical cystectomy (RC) for muscle-
invasive bladder cancer (MIBC) will succumb to metastatic disease. We summarize the …

Adjuvant and neoadjuvant approaches for urothelial cancer: Updated indications and controversies

F Massari, M Santoni, V di Nunno, L Cheng… - Cancer Treatment …, 2018 - Elsevier
Urothelial carcinoma (UC) of the bladder and upper urinary tract still results an open
challenge for clinical oncologists. Excluding selected patients who will particularly benefit …

National Surgical Quality Improvement Program surgical risk calculator poorly predicts complications in patients undergoing radical cystectomy with urinary diversion

S Golan, MA Adamsky, SC Johnson, NS Barashi… - … Oncology: Seminars and …, 2018 - Elsevier
Purpose To evaluate the accuracy of the American College of Surgeons National Surgical
Quality Improvement Programs (ACS-NSQIP) surgical risk calculator in patients undergoing …

Feasibility of cisplatin-based neoadjuvant chemotherapy in muscle-invasive bladder cancer patients with diminished renal function

VS Koshkin, PC Barata, LA Rybicki, H Zahoor… - Clinical genitourinary …, 2018 - Elsevier
Background Cisplatin-based neoadjuvant chemotherapy (NAC) before radical cystectomy is
the standard of care in muscle-invasive bladder cancer. There are limited data regarding …

[HTML][HTML] Emerging biomarkers and targeted therapies in urothelial carcinoma

P Mendiratta, P Grivas - Annals of Translational Medicine, 2018 - ncbi.nlm.nih.gov
The use of immunotherapy has revolutionized the management of patients with locally
advanced, unresectable, and metastatic urothelial carcinoma (UC); however, platinum …