Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

JA Batsis, DT Villareal - Nature Reviews Endocrinology, 2018 - nature.com
The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

Sarcopenic obesity: time to meet the challenge

R Barazzoni, S Bischoff, Y Boirie, L Busetto… - Obesity facts, 2018 - karger.com
The prevalence of overweight and obesity has reached epidemic proportions worldwide due
to increasingly pervasive obesogenic lifestyle changes. Obesity poses unprecedented …

Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity

KH Collins, W Herzog, GZ MacDonald… - Frontiers in …, 2018 - frontiersin.org
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …

The effects of obesity on skeletal muscle contractile function

J Tallis, RS James… - Journal of Experimental …, 2018 - journals.biologists.com
Obesity can cause a decline in contractile function of skeletal muscle, thereby reducing
mobility and promoting obesity-associated health risks. We reviewed the literature to …

Muscle mass, BMI, and mortality among adults in the United States: A population-based cohort study

MK Abramowitz, CB Hall, A Amodu, D Sharma… - PloS one, 2018 - journals.plos.org
Background The level of body-mass index (BMI) associated with the lowest risk of death
remains unclear. Although differences in muscle mass limit the utility of BMI as a measure of …

Domain management approach to heart failure in the geriatric patient: present and future

EZ Gorodeski, P Goyal, SL Hummel… - Journal of the American …, 2018 - jacc.org
Heart failure (HF) is a quintessential geriatric cardiovascular condition, with more than 50%
of hospitalizations occurring in adults age 75 years or older. In older patients, HF is closely …

Addressing obesity in aging patients

JA Batsis, AB Zagaria - Medical Clinics, 2018 - medical.theclinics.com
By the year 2030 in the United States, more than 20% of the population will be more than 65
years of age 1 (Fig. 1), up from 15% of the population now. 2 The fastest growing …

Health‐related quality of life and fall risk associated with age‐related body composition changes; sarcopenia, obesity and sarcopenic obesity

ZA Öztürk, İH Türkbeyler, A Abiyev, S Kul… - Internal medicine …, 2018 - Wiley Online Library
Background Sarcopenia, obesity, and sarcopenic obesity are various features of the ageing
process that can cause important health issues. The present study was undertaken to …

Sarcopenic obesity in cirrhosis—the confluence of 2 prognostic titans

T Eslamparast, AJ Montano‐Loza, M Raman… - Liver …, 2018 - Wiley Online Library
Sarcopenia and obesity are 2 major health conditions with a growing prevalence in
cirrhosis. The concordance of these 2 conditions, sarcopenic obesity, is associated with …

The impact of sarcopenic obesity on knee and hip osteoarthritis: a scoping review

K Godziuk, CM Prado, LJ Woodhouse… - BMC musculoskeletal …, 2018 - Springer
Background The progressive, debilitating nature of knee and hip osteoarthritis can result in
severe, persistent pain and disability, potentially leading to a need for total joint arthroplasty …