The pathogenesis of psoriatic arthritis
DJ Veale, U Fearon - The Lancet, 2018 - thelancet.com
Psoriatic arthritis is a chronic, immune-mediated, inflammatory arthropathy that presents with
inflammation of the joints and entheses, including those of the axial skeleton, and is …
inflammation of the joints and entheses, including those of the axial skeleton, and is …
Pathogenic stromal cells as therapeutic targets in joint inflammation
SG Dakin, M Coles, JP Sherlock, F Powrie… - Nature reviews …, 2018 - nature.com
Abstract Knowledge of how the joint functions as an integrated unit in health and disease
requires an understanding of the stromal cells populating the joint mesenchyme, including …
requires an understanding of the stromal cells populating the joint mesenchyme, including …
The oncostatin M‐stromal cell axis in health and disease
The field of stromal immunology has risen to prominence in the last decade, fuelled by
accumulating evidence that nonhaematopoietic mesenchymal cells are not simply involved …
accumulating evidence that nonhaematopoietic mesenchymal cells are not simply involved …
The role of extracellular nucleic acids in rheumatoid arthritis
E Neumann, R Hasseli, U Lange… - Current …, 2018 - ingentaconnect.com
Chronic inflammation, synovial hyperplasia, and local hypoxia lead to synovial cell
activation causing severe joint damage in chronic-inflammatory rheumatoid arthritis (RA) …
activation causing severe joint damage in chronic-inflammatory rheumatoid arthritis (RA) …
AB0138 The bone marrow oedema is linked to a osteoclastic environment in bone marrow during collagen induced mice arthritis development
W Tan, W Xuan, Q Wu, A Luo, W Yan, F Wang - 2018 - ard.bmj.com
Background Bone erosion is a central pathogenic event in Rheumatoid arthritis (RA) and is
associated with joint damage and poor functional outcome. The synovitis is traditionally …
associated with joint damage and poor functional outcome. The synovitis is traditionally …
3, 5-Di-C-β-D-glucopyranosyl phloroacetophenone, a major component of Melicope ptelefolia, suppresses fibroblast activation and alleviates arthritis in a mouse …
HJ Kim, JH Choi, JH Hwang… - International …, 2018 - spandidos-publications.com
Melicope ptelefolia has been traditionally used to treat rheumatism and fever. The present
study aimed to investigate the therapeutic effect of 3, 5‑di‑C‑β‑D‑glucopyranosyl …
study aimed to investigate the therapeutic effect of 3, 5‑di‑C‑β‑D‑glucopyranosyl …
Tumour necrosis factor: out of my heart!
L Vereecke, D Elewaut - Annals of the Rheumatic Diseases, 2018 - ard.bmj.com
Increasing evidence points to cardiovascular comorbidities in patients with rheumatic
diseases, particularly in rheumatoid arthritis (RA) and spondyloarthritis (SpA). 1 Ischaemic …
diseases, particularly in rheumatoid arthritis (RA) and spondyloarthritis (SpA). 1 Ischaemic …
The Role of IL‐6RA in UHMWPE Promotes Proliferation in Fibro‐Like Synovial Cells
X Pang, J Yang, X Zhen, H Nie, H Qin… - BioMed Research …, 2018 - Wiley Online Library
UHMWPE granule could induce macrophages and inflammatory responses in interfacial
tissues, which eliminated the wear debris of UHMWPE component and further induced …
tissues, which eliminated the wear debris of UHMWPE component and further induced …
Isolation, characterization and myogenic differentiation of synovial mesenchymal stem cells
Background: Synovial membrane represents a worthy source of mesenchymal stem cells
(MSCs). Synovial membrane derived stem cells has been described as encouraging line of …
(MSCs). Synovial membrane derived stem cells has been described as encouraging line of …
THU0099 Myeloid sirtuin 6 deficiency accelerates experimental and human arthritis by increasing macrophage infiltration into synovium
YS Suh, YH Cheon, MY Kim, SJ Woo, HS Noh, BH Park… - 2018 - ard.bmj.com
Background Rheumatoid arthritis (RA) is an autoimmune inflammatory disease of the joints
and is characterised by immune cell infiltration, synovial hyperplasia, and destruction of …
and is characterised by immune cell infiltration, synovial hyperplasia, and destruction of …