Cellular Uptake and Mode-of-Action of Clostridium difficile Toxins

P Papatheodorou, H Barth, N Minton… - Updates on Clostridium …, 2018 - Springer
Research on the human gut pathogen Clostridium difficile and its toxins has gained much
attention, particularly as a consequence of the increasing threat to human health presented …

Development of Neutralizing and Non-neutralizing Antibodies Targeting Known and Novel Epitopes of TcdB of Clostridioides difficile

V Fühner, PA Heine, S Helmsing, S Goy… - Frontiers in …, 2018 - frontiersin.org
Clostridioides difficile is the causative bacterium in 15–20% of all antibiotic associated
diarrheas. The symptoms associated with C. difficile infection (CDI) are primarily induced by …

[图书][B] Clostridium difficile Toxins: Entry and Uptake

Z Zhang - 2018 - search.proquest.com
Clostridium difficile is a major nosocomial pathogen that causes hospital-acquired and
antibiotic-associated diarrhea through the actions of two related exotoxins (TcdA and TcdB) …

[PDF][PDF] Understanding the genetic mechanisms of Clostridium difficile toxin regulation and clinical relapse

MM Lister - 2018 - core.ac.uk
Clostridium difficile is the leading cause of health care associated diarrhoea and remains a
burden for the NHS. Disease symptoms can range from mild diarrhoea through to fulminant …

Studying Protein–Glycolipid Interactions and Membrane Peptides and Proteins using Electrospray Ionization Mass Spectrometry and Model Membranes

J Li - 2018 - era.library.ualberta.ca
Membrane systems, including glycolipids (GLs) and membrane peptides and proteins
(MPs), play an important role in many cellular processes, such as singling, cellular …

Inflammation associée aux infections à Clostridium difficile: rôle des flagelles et régulation par les microARN

H Kobeissy - 2018 - theses.fr
Résumé Clostridium difficile (CD) représente la première cause d'infections digestives
nosocomiales dans les pays développés. Les infections à CD (ICD) induisent une …

Mechanisms of clostridial toxin binding and translocation

GS Lambert - 2018 - mospace.umsystem.edu
The bacterial genus Clostridium consists of over 150 species of anaerobic, fermentative,
spore-forming bacilli. Clostridial species produce up to 20% of all known bacterial exotoxins …

ベズロトクスマブ「ジーンプラバ® 点滴静注625 mg: クロストリジウム・ディフィシル感染症の再発抑制薬」 の薬理作用と臨床試験成績

木下潔 - 日本薬理学雑誌, 2018 - jstage.jst.go.jp
抄録 Clostridium difficile (C. difficile) は腸内常在菌でもあり, 抗菌薬治療等により腸内細菌叢が
破壊された後に腸内に繁茂し, 強毒素であるトキシン A 及びトキシン B (TcdA 及び TcdB) …