Troxerutin down-regulates KIM-1, modulates p38 MAPK signaling, and enhances renal regenerative capacity in a rat model of gentamycin-induced acute kidney injury

SA Salama, HH Arab, IA Maghrabi - Food & function, 2018 - pubs.rsc.org
Gentamycin is an aminoglycoside antibiotic that is widely employed for controlling Gram
negative bacterial infections including that caused by the antibiotic-resistant Pseudomonas …

Rare variants in drug target genes contributing to complex diseases, phenome-wide

SS Verma, N Josyula, A Verma, X Zhang, Y Veturi… - Scientific reports, 2018 - nature.com
The DrugBank database consists of~ 800 genes that are well characterized drug targets.
This list of genes is a useful resource for association testing. For example, loss of function …

Investigating Computational Methods to Model the Genotypic and Phenotypic Complexity of Adverse Health Outcomes: Understanding Undercover Heritability

SS Verma - 2018 - etda.libraries.psu.edu
Genome-wide association studies (GWAS) are the most popular and widely conducted
experiments to understand the genetic architecture of common diseases. Though GWAS …