Applications of the FIV model to study HIV pathogenesis

C Miller, Z Abdo, A Ericsson, J Elder, S VandeWoude - Viruses, 2018 - mdpi.com
Feline immunodeficiency virus (FIV) is a naturally-occurring retrovirus that infects domestic
and non-domestic feline species, producing progressive immune depletion that results in an …

Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules

SK Nissen, M Christiansen, M Helleberg, K Kjær… - Scientific Reports, 2018 - nature.com
Abstract Common CCR5-∆ 32 and HLA alleles only explain a minority of the HIV long-term
non-progressor (LTNP) and elite controller (EC) phenotypes. To identify rare genetic …

Marginal effects of systemic CCR5 blockade with maraviroc on oral simian immunodeficiency virus transmission to infant macaques

E Brocca-Cofano, C Xu, KS Wetzel, ML Cottrell… - Journal of …, 2018 - Am Soc Microbiol
Current approaches do not eliminate all human immunodeficiency virus type 1 (HIV-1)
maternal-to-infant transmissions (MTIT); new prevention paradigms might help avert new …

Development of a novel lentiviral vaccine vector and characterisation of in vitro immune responses

RK McLean - 2018 - era.ed.ac.uk
Vaccines are a highly effective means of preventing infectious disease. However, for many
diseases of livestock the available vaccines are ineffective or sub-optimal. This is partly due …

[图书][B] The Effects of HIV-1, HCV and Ebola Virus Envelope Proteins on Modulating Viral Phenotypes and Activity

LGA McKay - 2018 - search.proquest.com
The aim of this thesis is to present original research concerning co-infection between human
immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) as well as HIV-1 and …

Sequential adeno-associated virus deliverd HIV-1 subtype C ENV glycoproteins as novel vaccine immunogens

M Moodie - wiredspace.wits.ac.za
An efficacious HIV-1 vaccine that can elicit broadly neutralizing antibodies (bNAbs) targeting
the HIV-1 envelope glycoprotein (Env) is likely to provide protection from infection. To date …

БИОЛОГИЯ ВИЧ-ИНФЕКЦИИ. ЧАСТЬ 1. РЕЦЕПТОРНЫЕ МОЛЕКУЛЫ И СВЯЗЫВАНИЕ ВИЧ С КЛЕТКОЙ-МИШЕНЬЮ

ГО Гудима, РМ Хаитов - Физиология и патология иммунной системы, 2018 - elibrary.ru
Исследования процессов проникновения вируса иммунодефицита человека (ВИЧ) в
организм человека, взаимодействия вируса с клетками-мишенями и патогенеза инфек …

Mosquito Transmission of HIV: Rare or Not Possible?

D Nora - Mosquito-borne Diseases: Implications for Public …, 2018 - Springer
From its outbreak till today, HIV (human immunodeficiency virus) caused over 35 million
dead. If the transmission of the virus would not be restricted to unprotected sexual contact …

Identification and Characterization of HIV-1 antagonists to the antiviral protein, HERC5

DS Kochar - 2018 - search.proquest.com
Interferons that trigger the release of innate antiviral proteins are a vital immune defense
mechanism against viruses such as HIV-1. HERC5, an interferon stimulated protein inhibits …

[PDF][PDF] Precise and sustained gene silencing in CD4+ cells using designer epigenome modifiers as a therapeutic approach to treat HIV infection

T Mlambo - 2018 - d-nb.info
The human immunodeficiency virus (HIV) is a major global health burden which has claimed
over 25 million lives in the past 30 years. Although the current treatment strategies have …