Ophthalmic drug delivery systems for antibiotherapy—A review

M Dubald, S Bourgeois, V Andrieu, H Fessi - Pharmaceutics, 2018 - mdpi.com
The last fifty years, ophthalmic drug delivery research has made much progress, challenging
scientists about the advantages and limitations of this drug delivery approach. Topical eye …

Production, properties, and applications of solid self-emulsifying delivery systems (S-SEDS) in the food and pharmaceutical industries

A Gonçalves, N Nikmaram, S Roohinejad… - Colloids and Surfaces A …, 2018 - Elsevier
The food and pharmaceutical industries aim to develop innovative delivery systems to meet
the increasing consumer demand for healthier and safer food products and to improve the …

[HTML][HTML] Ocular administration of acetazolamide microsponges in situ gel formulations

MM Obiedallah, AM Abdel-Mageed… - Saudi Pharmaceutical …, 2018 - Elsevier
In the present work, the antiglaucoma drug, acetazolamide, was formulated as
microsponges in situ gel for ocular drug delivery aiming an improved therapeutic efficacy …

Sustained ocular delivery of Dorzolamide-HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and in-vivo pharmacodynamic …

NH Fouda, RT Abdelrehim, DA Hegazy, BA Habib - Drug delivery, 2018 - Taylor & Francis
Glaucoma is the second cause of blindness worldwide. Frequent administration of traditional
topical dosage forms may lead to patient incompliance and failure of treatment. Our study …

Application of nanoemulsions in drug delivery

K Pathak, S Pattnaik, K Swain - Nanoemulsions, 2018 - Elsevier
Nanoemulsions are being increasingly utilized as drug delivery systems for the effective
administration of pharmaceuticals because of their potential advantages over other …

Formulation optimization and the absorption mechanisms of nanoemulsion in improving baicalin oral exposure

L Wu, Y Bi, H Wu - Drug development and industrial pharmacy, 2018 - Taylor & Francis
Objective: The aim of this study was to optimize baicalin nanoemulsion, clarify the
absorption mechanisms of nanoemulsion improving the exposure of baicalin, and assess …

Formulation and ex vivoin vivo evaluation of pH-triggered brimonidine tartrate in situ gel for the glaucoma treatment using application of 32 factorial design

RK Barse, AA Tagalpallewar, CR Kokare… - Drug Development …, 2018 - Taylor & Francis
Context: Short residence time, poor bioavailability and poor permeability are the major
problems for conventional eye drops treatment. Objective: The aim of this article is to …

Increasing efficacy and reducing systemic absorption of brimonidine tartrate ophthalmic gels in rabbits

X Pang, J Li, J Pi, D Qi, P Guo, N Li… - Pharmaceutical …, 2018 - Taylor & Francis
Systemic absorption of ocularly administered Brimonidine Tartrate has been reported to give
rise to several side-effects. Hence, it has become crucial to develop a delivery system that …

Formation of nanoemulsion containing ibuprofen by PIC method for topical delivery

N Salim, MJ García-Celma, E Escribano, J Nolla… - Materials Today …, 2018 - Elsevier
This study reports the formation of nanoemulsions from palm-kernel oil esters
(PKOE)/Cremophor EL/water systems intended for topical administration of a non-steroidal …

Nanoemulsion in drug delivery

MR Patel, RB Patel, SD Thakore - Applications of nanocomposite materials …, 2018 - Elsevier
As technology is moving ahead with breakthrough inventions in pharmaceutical sector,
scientific community is confronted by ample of challenges for successfully establishing the …