[HTML][HTML] Blood-based cancer biomarkers in liquid biopsy: a promising non-invasive alternative to tissue biopsy

J Marrugo-Ramírez, M Mir, J Samitier - International journal of molecular …, 2018 - mdpi.com
Cancer is one of the greatest threats facing our society, being the second leading cause of
death globally. Currents strategies for cancer diagnosis consist of the extraction of a solid …

Molecular mechanisms of the preventable causes of cancer in the United States

EA Golemis, P Scheet, TN Beck… - Genes & …, 2018 - genesdev.cshlp.org
Abstract Annually, there are 1.6 million new cases of cancer and nearly 600,000 cancer
deaths in the United States alone. The public health burden associated with these numbers …

Detection and localization of surgically resectable cancers with a multi-analyte blood test

JD Cohen, L Li, Y Wang, C Thoburn, B Afsari… - Science, 2018 - science.org
Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can
detect eight common cancer types through assessment of the levels of circulating proteins …

Risk of neoplastic progression in individuals at high risk for pancreatic cancer undergoing long-term surveillance

MI Canto, JA Almario, RD Schulick, CJ Yeo, A Klein… - Gastroenterology, 2018 - Elsevier
Background & Aims Screening of individuals who have a high risk of pancreatic ductal
adenocarcinoma (PDAC), because of genetic factors, frequently leads to identification of …

Platelet–leukocyte hybrid membrane‐coated immunomagnetic beads for highly efficient and highly specific isolation of circulating tumor cells

L Rao, QF Meng, Q Huang, Z Wang… - Advanced Functional …, 2018 - Wiley Online Library
Biomimetic cell‐membrane‐camouflaged nanoparticles with desirable features have been
widely used for various biomedical applications. However, the current research focuses on …

[HTML][HTML] Repeated mutKRAS ctDNA measurements represent a novel and promising tool for early response prediction and therapy monitoring in advanced pancreatic …

S Kruger, V Heinemann, C Ross, F Diehl, D Nagel… - Annals of …, 2018 - Elsevier
Background The presence of mutated KRAS (mut KRAS ctDNA) in plasma samples has
been consistently shown to be a negative prognostic indicator in pancreatic cancer (PC) …

Novel SERS labels: Rational design, functional integration and biomedical applications

B Shan, Y Pu, Y Chen, M Liao, M Li - Coordination Chemistry Reviews, 2018 - Elsevier
Driven by the growing demand for healthcare and point-of-care test applications, next-
generation diagnostic tools of diseases require sensing platforms that enable rapid …

[HTML][HTML] Cancer diagnosis using a liquid biopsy: challenges and expectations

F Castro-Giner, S Gkountela, C Donato, I Alborelli… - Diagnostics, 2018 - mdpi.com
The field of cancer diagnostics has recently been impacted by new and exciting
developments in the area of liquid biopsy. A liquid biopsy is a minimally invasive alternative …

A versatile label-free electrochemical biosensor for circulating tumor DNA based on dual enzyme assisted multiple amplification strategy

HF Wang, RN Ma, F Sun, LP Jia, W Zhang… - Biosensors and …, 2018 - Elsevier
A versatile label-free electrochemical biosensor based on dual enzyme assisted multiple
amplification strategy was developed for ultrasensitive detection of circulating tumor DNA …

Colorectal cancer prevention: immune modulation taking the stage

R Fletcher, YJ Wang, RE Schoen, OJ Finn, J Yu… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Prevention or early detection is one of the most promising strategies against colorectal
cancer (CRC), the second leading cause of cancer death in the US. Recent studies indicate …