Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison

J Feld, V Chandran, N Haroon, R Inman… - Nature Reviews …, 2018 - nature.com
Ankylosing spondylitis (AS) was first identified in the late 17th century. 250 years later,
inflammatory spine disease was recognized to be one of the patterns of psoriatic arthritis …

Psoriasis in skin of color: insights into the epidemiology, clinical presentation, genetics, quality-of-life impact, and treatment of psoriasis in non-white racial/ethnic …

BP Kaufman, AF Alexis - American Journal of Clinical Dermatology, 2018 - Springer
Psoriasis is a chronic inflammatory skin condition affecting diverse racial/ethnic groups
throughout the world. Large population-based studies suggest that psoriasis occurs most …

Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis

A Chandra, S Senapati, S Roy, G Chatterjee… - Clinical …, 2018 - Springer
Background Psoriasis is a chronic inflammatory autoimmune skin disorder. Several studies
suggested psoriasis to be a complex multifactorial disease, but the exact triggering factor is …

Differential efficacy of biologic treatments targeting the TNF-α/IL-23/IL-17 axis in psoriasis and psoriatic arthritis

K Furue, T Ito, M Furue - Cytokine, 2018 - Elsevier
Psoriasis and psoriatic arthritis cause significant physical and psychological burdens for
afflicted individuals. An accelerated TNF-α/IL-23/IL-17 axis is their major pathomechanism; …

Human leukocyte antigen-class I alleles and the autoreactive T cell response in psoriasis pathogenesis

JC Prinz - Frontiers in immunology, 2018 - frontiersin.org
Psoriasis is a complex immune-mediated inflammatory skin disease characterized by T-cell-
driven epidermal hyperplasia. It occurs on a strong genetic predisposition. The human …

Autoimmunity and autoimmune co‐morbidities in psoriasis

K Furue, T Ito, G Tsuji, T Kadono, T Nakahara… - …, 2018 - Wiley Online Library
Psoriasis is characterized by widespread scaly erythematous plaques that cause significant
physical and psychological burdens for the affected individuals. Accelerated inflammation …

Pharmacogenetics and pharmacogenomics in moderate-to-severe psoriasis

MC Ovejero-Benito, E Munoz-Aceituno… - American Journal of …, 2018 - Springer
Pharmacogenetics is the study of variations in DNA sequence related to drug response.
Moreover, the evolution of biotechnology and the sequencing of human DNA have allowed …

Infection's sweet tooth: how glycans mediate infection and disease susceptibility

SL Taylor, MA McGuckin, S Wesselingh… - Trends in microbiology, 2018 - cell.com
Glycans form a highly variable constituent of our mucosal surfaces and profoundly affect our
susceptibility to infection and disease. The diversity and importance of these surface glycans …

Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis

JJW Kuiper, J Setten, M Devall… - Human molecular …, 2018 - academic.oup.com
Abstract Birdshot Uveitis (Birdshot) is a rare eye condition that affects HLA-A29-positive
individuals and could be considered a prototypic member of the recently proposed 'MHC-I …

[HTML][HTML] Variants at HLA-A, HLA-C, and HLA-DQB1 confer risk of psoriasis vulgaris in Japanese

J Hirata, T Hirota, T Ozeki, M Kanai, T Sudo… - Journal of investigative …, 2018 - Elsevier
Psoriasis vulgaris (PsV) is an autoimmune disease of skin and joints with heterogeneity in
epidemiologic and genetic landscapes of global populations. We conducted an initial …