Endophytic fungi—alternative sources of cytotoxic compounds: a review
Cancer is a major cause of death worldwide, with an increasing number of cases being
reported annually. The elevated rate of mortality necessitates a global challenge to explore …
reported annually. The elevated rate of mortality necessitates a global challenge to explore …
Evidence for the involvement of the master transcription factor NF-κB in cancer initiation and progression
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the
regulation of a large number of genes that are involved in important physiological …
regulation of a large number of genes that are involved in important physiological …
Novel 1, 3, 4-oxadiazole induces anticancer activity by targeting NF-κB in hepatocellular carcinoma cells
CD Mohan, NC Anilkumar, S Rangappa… - Frontiers in …, 2018 - frontiersin.org
Aberrant activation of NF-κB is linked with the progression of human malignancies including
hepatocellular carcinoma (HCC), and blockade of NF-κB signaling could be a potential …
hepatocellular carcinoma (HCC), and blockade of NF-κB signaling could be a potential …
N-substituted pyrido-1, 4-oxazin-3-ones induce apoptosis of hepatocellular carcinoma cells by targeting NF-κB signaling pathway
CD Mohan, H Bharathkumar, Dukanya… - Frontiers in …, 2018 - frontiersin.org
Hepatocellular carcinoma (HCC) is a fatal disease and ranked fifth in cancer related
mortality. Persistent activation of NF-κB is responsible for the oncogenesis, metastasis …
mortality. Persistent activation of NF-κB is responsible for the oncogenesis, metastasis …
Targeting DNA binding for NF-κB as an anticancer approach in Hepatocellular Carcinoma
Quinoline core has been shown to possess a promising role in the development of
anticancer agents. However, the correlation between its broad spectrum of bioactivity and …
anticancer agents. However, the correlation between its broad spectrum of bioactivity and …
1, 3-Diphenylpropanes from Daphne giraldii induced apoptosis in hepatocellular carcinoma cells through nuclear factor kappa-B inhibition
GD Yao, Q Sun, XY Song, XX Huang, Y Zhang… - Bioorganic …, 2018 - Elsevier
Abstract One new 1, 3-diphenylpropane (1) together with six known analogues (2–7) were
firstly isolated from the stem and root bark of Daphne giraldii. Their structures were …
firstly isolated from the stem and root bark of Daphne giraldii. Their structures were …