Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of
depression and related disorders. The ability to promote both structural and functional …

Depression and anxiety are psychiatric diagnoses commonly associated with low quality of
life and low percentage of responsiveness by patients treated with currently available drugs …

Scaffolding proteins represent an evolutionary solution to controlling the specificity of
information transfer in intracellular networks. They are highly concentrated in complexes …

Ayahuasca ingestion modulates brain activity, neurotransmission, gene expression and
epigenetic regulation. N, N-Dimethyltryptamine (DMT, one of the alkaloids in Ayahuasca) …

The classic serotonergic hallucinogens, or psychedelics, have the ability to profoundly alter
perception and behavior. These can include visual distortions, hallucinations, detachment …

Recent reports on the effects of psychedelic-assisted therapies for mood disorders and
addiction, as well as the effects of psychedelics in the treatment of cluster headache, have …

The chapter focuses on the mechanisms through which the serotoninergic system can
induce hallucinations, altering sensory perceptive functions. The hallucinogenic activity of …

Schizophrenia is a psychiatric disorder that affects 1% of the population worldwide. The
serotonin and glutamate receptor systems have been implicated in schizophrenia and its …

The use of peptide drugs has gained popularity recently. Peptides are attractive drug targets
due to their high specificity and potency towards their biological targets. A drawback for …

Schizophrenia is a psychiatric disorder that affects 1% of the population worldwide. The
serotonin and glutamate receptor systems have been implicated in schizophrenia and its …