Highlights•Mass cytometry's niche within cutting edge single cell analysis
methods.•Unbiased analysis of lymphoid and myeloid immune cell diversity.•Simultaneous …

Secondary lymphoid organs (SLO), including the spleen and lymph nodes (LN) are a
meeting place for immune cells to initiate adaptive immune responses. Lymphocytes …

Abstract Background & Aims The natural outcomes of hepatitis C virus (HCV) as well as the
progression of the liver disease are highly variable and depend primarily on an efficient …

Chronic hepatitis C virus (HCV) infection appears to trigger the onset of immune exhaustion
and apoptosis to potentially assist viral persistence inside the host, eventually leading to …

Hepatitis B virus (HBV)‐specific CD8+ T cells play an important role in the clearance of HBV
infection. Programmed cell death‐1 (PD‐1), an immunosuppressive molecule that regulates …

Although hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency
virus (HIV) are ubiquitous in medicine today and in the general public's consciousness, the …

Aim Interferon‐free direct‐acting antiviral (DAA) therapy is an effective treatment for chronic
hepatitis C (CH (C)) patients. Activity of natural killer (NK) cells was reported to be impaired …

Current immunosuppression regimens in organ transplantation primarily inhibit T cells.
However, T cells are also critical in protective immunity, especially in immune-compromised …

Clearance of hepatitis C virus (HCV) is dependent on an effective virus‐specific CD 8+ T‐
cell response, which is dysfunctional in chronic HCV infection. Dysfunction in bulk or non …

The transcription factor FOXP3 is an essential marker of the development and activation of
regulatory T cells (Tregs), which are cells specialized in the regulation and normal tolerance …