The discrimination ratio derived from novel object recognition tasks as a measure of recognition memory sensitivity, not bias
MH Sivakumaran, AK Mackenzie, IR Callan, JA Ainge… - Scientific reports, 2018 - nature.com
Translational recognition memory research makes frequent use of the Novel Object
Recognition (NOR) paradigm in which animals are simultaneously presented with one new …
Recognition (NOR) paradigm in which animals are simultaneously presented with one new …
Dissociable contributions of thalamic nuclei to recognition memory: novel evidence from a case of medial dorsal thalamic damage
The thalamic nuclei are thought to play a critical role in recognition memory. Specifically, the
anterior thalamic nuclei and medial dorsal nuclei may serve as critical output structures in …
anterior thalamic nuclei and medial dorsal nuclei may serve as critical output structures in …
Immunotherapy to improve cognition and reduce pathological species in an Alzheimer's disease mouse model
K Herline, F Prelli, P Mehta, C MacMurray… - Alzheimer's Research & …, 2018 - Springer
Background Alzheimer's disease (AD) is characterized by physiologically endogenous
proteins amyloid beta (Aβ) and tau undergoing a conformational change and accumulating …
proteins amyloid beta (Aβ) and tau undergoing a conformational change and accumulating …
Longitudinal evaluation of Tau‐P301L transgenic mice reveals no cognitive impairments at 17 months of age
BA Kent, CJ Heath, CH Kim, R Ahrens… - Brain and …, 2018 - Wiley Online Library
Introduction Tau is a microtubule‐associated binding protein implicated in
neurodegenerative tauopathies, including frontotemporal dementia (FTD) and Alzheimer's …
neurodegenerative tauopathies, including frontotemporal dementia (FTD) and Alzheimer's …
Midday meals do not impair mouse memory
SC Power, MJ Michalik, S Couture-Nowak, BA Kent… - Scientific Reports, 2018 - nature.com
Nocturnal mice fed in the middle of the light period exhibit food anticipatory rhythms of
behavior and physiology under control of food-entrainable circadian clocks in the brain and …
behavior and physiology under control of food-entrainable circadian clocks in the brain and …
The Contribution of Recollection, Familiarity and Discrimination to Object Recognition Deficits in Advanced Age
Declines in object recognition are widely reported in older humans and animal models, but
the exact nature of these deficits remains a topic of debate. Accumulating data over the past …
the exact nature of these deficits remains a topic of debate. Accumulating data over the past …
The Value of the Object Recognition Paradigm in Investigating Animal Models of Alzheimer's Disease: Advances and Future Directions
C Mathis - Handbook of Behavioral Neuroscience, 2018 - Elsevier
A number of animal models have been designed to reproduce some or the main
pathophysiological and behavioural characteristics of Alzheimer's disease (AD), and to …
pathophysiological and behavioural characteristics of Alzheimer's disease (AD), and to …
Perirhinal cortex lesions and spontaneous object recognition memory in rats: Detecting novelty but not distinguishing novelty
JP Aggleton - Handbook of Behavioral Neuroscience, 2018 - Elsevier
Perirhinal cortex lesions in rats consistently impair object recognition memory, as shown by
the failure to spend more time exploring a novel object in preference to a familiar object in a …
the failure to spend more time exploring a novel object in preference to a familiar object in a …
Passive Immunization to Improve Cognition and Reduce Pathological Species in a Mouse Model of Alzheimer's Disease
K Herline - 2018 - search.proquest.com
Alzheimer's disease (AD) is characterized by physiologically endogenous proteins, amyloid
beta (Aβ) and tau, undergoing a conformational change and accumulating as soluble …
beta (Aβ) and tau, undergoing a conformational change and accumulating as soluble …