Abstract Three-dimensional (3D) in vitro neural tissue models provide a better recapitulation
of in vivo cell-cell and cell-extracellular matrix interactions than conventional two …

Despite advances in breast cancer diagnosis and treatment, many patients still fail therapy,
resulting in disease progression, recurrence, and reduced overall survival. Historically …

Modifiable hydrogels have revealed tremendous insight into how physical characteristics of
cells' 3D environment drive stem cell lineage specification. However, in native tissues, cells …

Cell culture is an indispensable in vitro tool used to improve our perception and
understanding of cell biology, the development of tissue engineering, tissue morphology …

Doxorubicin (DOX) is the most effective chemotherapeutic drug developed against broad
range of cancers such as solid tumours, transplantable leukemias and lymphomas …

Research on human induced pluripotent stem cells (hiPSCs) is one of the fastest growing
fields in biomedicine. Generated from patient's own somatic cells, hiPSCs can be …

Conventional 2D cell culture techniques have provided fundamental insights into key
biochemical and biophysical mechanisms responsible for various cellular behaviors, such …

Many attempts have been made to repair articular cartilage defects, including mesenchymal
stem cell (MSC)-based tissue engineering strategies. Although this approach shows …

The advancement and improvement in decellularization methods can be attributed to the
increasing demand for tissues and organs for transplantation. Decellularized tissues and …

Stem cells are a powerful resource for many applications including regenerative medicine,
patient-specific disease modeling, and toxicology screening. However, eliciting the desired …