Oncolytic virotherapy for breast cancer treatment

SM O'Bryan, JM Mathis - Current Gene Therapy, 2018 - ingentaconnect.com
Breast cancer continues to be a leading cause of mortality among women. While at an early
stage, localized breast cancer is easily treated; however, advanced stages of disease …

The role of oncolytic viruses in the treatment of melanoma

CAY Bayan, AT Lopez, RD Gartrell… - Current oncology …, 2018 - Springer
Abstract Purpose of Review Oncolytic virotherapy is a new approach to the treatment of
cancer and its success in the treatment of melanoma represents a breakthrough in cancer …

Inhibition of antigen presentation during AAV gene therapy using virus peptides

W Shao, X Chen, RJ Samulski… - Human Molecular …, 2018 - academic.oup.com
The clinical trial using adeno-associated virus (AAV) vector delivery of mini-dystrophin in
patients with Duchenne Muscular Dystrophy (DMD) demonstrated a cytotoxic lymphocyte …

[HTML][HTML] A novel oncolytic herpes simplex virus design based on the common overexpression of microRNA-21 in tumors

M Marzulli, L Mazzacurati, M Zhang… - Journal of gene …, 2018 - ncbi.nlm.nih.gov
Background: Recognition sequences for microRNAs (miRs) that are down-regulated in
tumor cells have recently been used to render lytic viruses tumor-specific. Since different …

[PDF][PDF] Co-infection prevalence of herpes simplex virus types 1 and 2 with human papillomavirus and associated risk factors among asymptomatic women in Ghana

AY Francis, D Oksana, DE Timmy, AH Richard… - Int. J. Infect. Dis …, 2018 - academia.edu
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are among the most common
human viral infections worldwide and associated with increased risk for other sexually …

Increasing antigen presentation on HSV-1-infected cells increases lesion size but does not alter neural infection or latency

TA Russell, T Velusamy, YY Tseng… - Journal of General …, 2018 - microbiologyresearch.org
CD8+ T cells have a role in the control of acute herpes simplex virus (HSV) infection and
may also be important in the maintenance of latency. In this study we have explored the …

[HTML][HTML] Oncolytic Herpes Simplex Virus ICP47 Deletion Reverses Tumor Immune Evasion

J Cheng, Y Wang, Y Zhang, W Cai, Y Zhou, Z Han… - Yangtze Medicine, 2018 - scirp.org
Herpes simplex virus (HSV) is an enveloped, double-stranded DNA virus that has been
used with modification as oncolytic viruses (OVs) against a number of tumor types. OVs …

[HTML][HTML] Rôle des protéines Dok-1 et Dok-2 dans l'infection par le virus de l'herpès simplex 1

S Lahmidi - 2018 - search.proquest.com
Le virus de l'herpès simplex-1 (VHS-1) affecte 80% de la population mondiale et son
infection est généralement associée à l'apparition de lésions au niveau de la muqueuse …

[图书][B] Modulation of tumor associated macrophages enhances oncolytic herpes virotherapy in preclinical models of Ewing sarcoma

NL Denton - 2018 - search.proquest.com
Ewing sarcoma is a highly aggressive bone and soft tissue cancer that is found
predominantly in adolescents and young adults. The aggressive progression of Ewing …

[图书][B] Evaluation of Oncolytic and Immunomodulatory Potential of the HSV-1 Live-Attenuated Vaccine Strain VC2 in an Immunocompetent Murine Melanoma Model

NW Fowlkes - 2018 - search.proquest.com
Melanoma accounts for 90% of skin cancer-related deaths in humans. Treatment options for
metastatic melanoma in people is very limited. Melanoma is considered to be an …