Between the 1930s and 50s, evolutionary biologists developed a successful theory of why
organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …

Mutations of a single gene can lead to a major increase in longevity in organisms ranging
from yeast and worms to insects and mammals. Discovering these mutations (sometimes …

Much has been learned about the genetics of aging from studies in model organisms, but
still little is known about naturally occurring alleles that contribute to variation in longevity …

Metabolic resistance to insecticides threatens malaria control. However, little is known about
its fitness cost in field populations of malaria vectors, thus limiting the design of suitable …

Aging is accompanied by a pervasive collapse of proteostasis, while reducing general
protein synthesis promotes longevity across taxa. Here, we show that the eIF4E isoform IFE …

The bionematicidal effect of a synthetic volatile mixture (SVM) of four volatile organic
compounds (VOCs) emitted by the endophytic fungus Daldinia cf. concentrica against the …

As demonstrated in various animal models, organismal longevity can be achieved via
interventions that at the mechanistic level could be considered to entail …

Standard evolutionary theories of aging postulate that reduced extrinsic mortality leads to
evolution of longevity. Clownfishes of the genus Amphiprion live in a symbiotic relationship …

Introduction: Aging is a complex biological process that brings about a gradual decline of
physiological and metabolic machineries as a result of maturity. Also, aging is irreversible …

The plant kingdom contains a large number of unique phytochemicals, some of which are
known to be beneficial to the function of human cells. Where the macroand micronutrients in …