[HTML][HTML] Natural killer cells: development, maturation, and clinical utilization

AM Abel, C Yang, MS Thakar… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

[HTML][HTML] Mechanisms of regulated and dysregulated CARD11 signaling in adaptive immunity and disease

JR Bedsaul, NM Carter, KE Deibel… - Frontiers in …, 2018 - frontiersin.org
CARD11 functions as a key signaling scaffold that controls antigen-induced lymphocyte
activation during the adaptive immune response. Somatic mutations in CARD11 are …

[HTML][HTML] Enhanced interaction between SEC2 mutant and TCR Vβ induces MHC II–independent activation of T cells via PKCθ/NF-κB and IL-2R/STAT5 signaling …

X Fu, M Xu, Y Song, Y Li, H Zhang, J Zhang… - Journal of Biological …, 2018 - ASBMB
SEC2, a major histocompatibility complex class II (MHC II)-dependent T-cell mitogen, binds
MHC II and T-cell receptor (TCR) Vβs to induce effective co-stimulating signals for clonal T …

Enhancement of natural killer activity and IFN-γ production in an IL-12-dependent manner by a Brassica rapa L.

K Yamamoto, K Furuya, K Yamada… - Bioscience …, 2018 - academic.oup.com
Certain food components possess immunomodulatory effects. The aim of this study was to
elucidate the mechanism of the immunostimulatory activity of Brassica rapa L. We …

[HTML][HTML] IQ domain-containing GTPase-activating protein 1 regulates cytoskeletal reorganization and facilitates NKG2D-mediated mechanistic target of rapamycin …

AM Abel, AA Tiwari, ZJ Gerbec, JR Siebert… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells are innate lymphocytes that play essential roles in mediating
antitumor immunity. NK cells respond to various inflammatory stimuli including cytokines and …

Dextran enhances the lentiviral transduction efficiency of murine and human primary NK cells

A Nanbakhsh, B Best, M Riese, S Rao, L Wang… - JoVE (Journal of …, 2018 - jove.com
The efficient transduction of specific genes into natural killer (NK) cells has been a major
challenge. Successful transductions are critical to defining the role of the gene of interest in …

The role of Neuropilin-1–FYN interaction in odontoblast differentiation of dental pulp stem cells

Y Song, P Cao, Z Gu, J Xiao, M Lian… - Cellular …, 2018 - liebertpub.com
Abnormal odontoblast differentiation of dental pulp stem cells (DPSCs) caused by
inflammation is closely related to the development of dental caries. Neuropilin-1 (NRP1) is …

[HTML][HTML] B-cell leukemia/lymphoma 10 promotes angiogenesis in an experimental corneal neovascularization model

G Liu, P Lu, L Chen, W Zhang, M Wang, D Li, X Zhang - Eye, 2018 - nature.com
Abstract Purpose Corneal neovascularization (CrNV) arises from many causes including
corneal inflammatory, infectious, or traumatic insult, and frequently leads to impaired vision …

[图书][B] Lineage Specific Role for Adhesion and Degranulation Promoting Adaptor Protein (ADAP) in iNKT Cell Development and Functions

TG Gohl - 2018 - search.proquest.com
Invariant natural killer T (iNKT) cells comprise a sub-lineage of T lymphocytes that express
an" invariant" T cell receptor (TCR) with specificity for glycolipid antigens when presented in …