[HTML][HTML] Role of miR-223 in the pathophysiology of liver diseases

D Ye, T Zhang, G Lou, Y Liu - Experimental & molecular medicine, 2018 - nature.com
MiRNAs are small, noncoding RNAs, which can regulate gene expression
posttranscriptionally, and they have emerged as key factors in disease biology by aiding in …

State of the art in microRNA as diagnostic and therapeutic biomarkers in chronic lymphocytic leukemia

H Mirzaei, S Fathullahzadeh… - Journal of cellular …, 2018 - Wiley Online Library
Early diagnostic is one of the most important steps in cancer therapy which helps to design
and choose a better therapeutic approach. The finding of biomarkers in various levels …

[HTML][HTML] MicroRNAs as new biomarkers for diagnosis and prognosis, and as potential therapeutic targets in acute myeloid leukemia

S Trino, D Lamorte, A Caivano, I Laurenzana… - International journal of …, 2018 - mdpi.com
Acute myeloid leukemias (AML) are clonal disorders of hematopoietic progenitor cells which
are characterized by relevant heterogeneity in terms of phenotypic, genotypic, and clinical …

The involvement of microRNAs in modulation of innate and adaptive immunity in systemic lupus erythematosus and lupus nephritis

M Honarpisheh, P Köhler… - Journal of …, 2018 - Wiley Online Library
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs), represent a family of RNA
molecules that do not translate into protein. Nevertheless, they have the ability to regulate …

[HTML][HTML] miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells

L Wan, X Yuan, M Liu, B Xue - Experimental and …, 2018 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is a major malignant tumor type with a high incidence and
mortality. Infection with hepatitis virus is a high‑risk factor. Previous studies have …

[HTML][HTML] The nefarious nexus of noncoding RNAs in cancer

E Anastasiadou, A Faggioni, P Trivedi… - International Journal of …, 2018 - mdpi.com
The past decade has witnessed enormous progress, and has seen the noncoding RNAs
(ncRNAs) turn from the so-called dark matter RNA to critical functional molecules …

RCA-enhanced multifunctional molecule beacon-based strand-displacement amplification for sensitive microRNA detection

H Xu, D Wu, Y Zhang, H Shi, C Ouyang, F Li… - Sensors and Actuators B …, 2018 - Elsevier
MicroRNAs (miRNAs) are regarded as promising cancer-related biomarkers. Here, we
developed a simple, sensitive and specific fluorescence method based on the combination …

[HTML][HTML] Role of microRNAs in renal parenchymal diseases—a new dimension

SK Shaffi, D Galas, A Etheridge… - International Journal of …, 2018 - mdpi.com
Since their discovery in 1993, numerous microRNAs (miRNAs) have been identified in
humans and other eukaryotic organisms, and their role as key regulators of gene expression …

Therapeutic applications of group I intron‐based trans‐splicing ribozymes

CH Lee, SR Han, SW Lee - Wiley Interdisciplinary Reviews …, 2018 - Wiley Online Library
Since the breakthrough discovery of catalytic RNAs (ribozymes) in the early 1980s, valuable
ribozyme‐based gene therapies have been developed for incurable diseases ranging from …

Prognostic role of microRNA-155 in patients with leukemia: A meta-analysis

X Zhang, Y Wang, Q Guo, Y Diao, H Liu, G Song… - Clinica Chimica …, 2018 - Elsevier
Background Recent studies have shown that microRNA-155 (miR-155) is correlated with
clinical outcomes of leukemia. This meta-analysis explores to evaluate the prognostic value …