Human parechovirus: an increasingly recognized cause of sepsis-like illness in young infants

L Olijve, L Jennings, T Walls - Clinical microbiology reviews, 2018 - Am Soc Microbiol
Human parechovirus (HPeV) is increasingly being recognized as a potentially severe viral
infection in neonates and young infants. HPeV belongs to the family Picornaviridae and is …

Intracranial hemorrhage in neonates: A review of etiologies, patterns and predicted clinical outcomes

AP Tan, P Svrckova, F Cowan, WK Chong… - European journal of …, 2018 - Elsevier
Intracranial hemorrhage (ICH) in neonates often results in devastating neurodevelopmental
outcomes as the neonatal period is a critical window for brain development. The …

Encephalitis in US children

K Messacar, M Fischer, SR Dominguez… - Infectious Disease …, 2018 - id.theclinics.com
Encephalitis is a rare but serious condition of neurologic dysfunction due to inflammation of
the brain parenchyma. A wide variety of infectious and noninfectious etiologies are …

Viral sepsis in children

N Gupta, R Richter, S Robert, M Kong - Frontiers in Pediatrics, 2018 - frontiersin.org
Sepsis in children is typically presumed to be bacterial in origin until proven otherwise, but
frequently bacterial cultures ultimately return negative. Although viruses may be important …

Parechovirus: an important emerging infection in young infants

PN Britton, CA Jones, K Macartney… - Medical Journal of …, 2018 - Wiley Online Library
Epidemics of human parechovirus (HPeV) causing disease in young children have occurred
every 2 years in Australia since 2013. HPeV genotype 3 caused the epidemic from late 2017 …

Epidemiology of sepsis-like illness in young infants: major role of enterovirus and human parechovirus

EP de Jong, MGA van den Beuken… - The Pediatric …, 2018 - journals.lww.com
Background: Sepsis-like illness is a main cause for hospital admission in young infants. Our
aim was to investigate incidence, epidemiology and clinical characteristics of enterovirus …

High prevalence of developmental concern amongst infants at 12 months following hospitalised parechovirus infection

PN Britton, G Khandaker, A Khatami… - … of Paediatrics and …, 2018 - Wiley Online Library
Aim The human parechovirus (HPeV) is an increasingly recognised cause of sepsis and
central nervous system infection in young infants for which there are limited long‐term …

Severe parechovirus 3 infections in young infants—Kansas and Missouri, 2014

CM Midgley, MA Jackson… - Journal of the …, 2018 - academic.oup.com
Background Infection with parechovirus type 3 (PeV3) can cause severe neurologic and
sepsis-like illness in young infants; clinical and epidemiologic descriptions have been …

Increased detection of human parechovirus infection in infants in England during 2016: epidemiology and clinical characteristics

LF Antolín, S Kadambari, S Braccio… - Archives of disease in …, 2018 - adc.bmj.com
Background Human parechovirus (HPeV), like enteroviruses, usually causes mild self-
limiting respiratory and gastrointestinal symptoms. In infants, HPeV can occasionally cause …

Human parechovirus meningitis with adverse neurodevelopmental outcome: a case report

MC Berk, AHL Bruning… - The Pediatric …, 2018 - journals.lww.com
Human parechovirus infections usually cause mild symptoms in children. Although their
contribution to severe disease in young children—such as neonatal sepsis and …