At the crossroads of clinical and preclinical research for muscular dystrophy—are we closer to effective treatment for patients?

KI Gawlik - International journal of molecular sciences, 2018 - mdpi.com
Among diseases affecting skeletal muscle, muscular dystrophy is one of the most
devastating and complex disorders. The term 'muscular dystrophy'refers to a heterogeneous …

Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy

P Mantuano, F Sanarica, E Conte, MG Morgese… - Biochemical …, 2018 - Elsevier
The pharmacological stimulation of AMP-activated protein kinase (AMPK) via metabolic
enhancers has been proposed as potential therapeutic strategy for Duchenne muscular …

Normalization of connexin 43 protein levels prevents cellular and functional signs of dystrophic cardiomyopathy in mice

JP Gonzalez, J Ramachandran, E Himelman… - Neuromuscular …, 2018 - Elsevier
Duchenne muscular dystrophy (DMD) associated cardiomyopathy remains incurable.
Connexin 43 (Cx43) is upregulated and remodeled in the hearts of mdx mice, a mouse …

The effect of wearing night splints for one year on the standing motor function of patients with Duchenne muscular dystrophy

H Nishizawa, A Matsukiyo, N Shiba… - Journal of Physical …, 2018 - jstage.jst.go.jp
[Purpose] To investigate the effect of night splints on the standing motor function and ankle
dorsiflexion angles of patients with Duchenne muscular dystrophy (DMD).[Subjects and …

Strength training for special populations

ME Pepin, JA Roche, MH Malek - Conditioning for Strength and …, 2018 - taylorfrancis.com
This chapter presents the various populations that will benefit from specific exercise
programs and demonstrates an understanding of the roles of strength training in different …

[PDF][PDF] Lihasdüstroofiad–Duchenne'i lihasdüstroofia ja selle füsioterapeutiline käsitlus

M Aas - core.ac.uk
Lihasdüstroofiad on grupp pärilikke haigusi, mille põhitunnuseks on progresseeruv
lihasnõrkus. Haigusel on 9 erinevat vormi, mis üksteisest teatud tunnuste poolest erinevad …