HPV-driven oropharyngeal cancers have significantly better survival rates than tobacco and
alcohol induced head and neck cancers. As HPV-positive patients are younger, healthier …

Immunoglobulin (Ig) G1 antibodies stimulate antibody-dependent cell-mediated cytotoxicity
(ADCC). Cetuximab, an IgG1 isotype monoclonal antibody, is a standard-of-care treatment …

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human
cancer and has an increasing annual incidence. Although most cSCC is cured with office …

The past several years have seen major advances in the use of systemic therapy for
treatment of patients with oral cancer. Systemic therapy refers to chemotherapy and …

Cancer of the head and neck (HNC) is a heterogeneous disease of the upper aerodigestive
tract, encompassing distinct histologic types, different anatomic sites, and human …

Despite the development of standard therapies, including surgery, radiotherapy and
chemotherapy, survival rates for head and neck squamous cell carcinoma (HNSCC) have …

Head and neck cancer (HNC) is a fatal malignancy with an overall long-term survival of
about 50% for all stages. The diagnosis is not rarely delayed, and the majority of patients …

Head and neck squamous cell carcinoma (HNSCC) is a common malignancy with high rates
of mortality and morbidity. Beginning with cetuximab, investigators continue to optimize …

One of the most known oncogenes is the epidermal growth factor receptor (EGFR) family. It
activates multiple signaling cascades that promote carcinogenesis and immune evasion …

Introduction: The majority of patients with locally advanced head and neck squamous cell
carcinoma (HNSCC) will recur. The treatment of patients with recurrent/metastatic (R/M …