Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo

DM Metwally, EM Al-Olayan, M Alanazi… - … and alternative medicine, 2018 - Springer
Background Schistosomiasis is an acute and chronic zoonotic parasitic disease caused by
trematode worms. The host inflammatory response to schistosome eggs leads to perioval …

[HTML][HTML] Enediyne-activated, EGFR-targeted human β-defensin 1 has therapeutic efficacy against non-small cell lung carcinoma

W Liu, K Zhu, J Xu, J Wang, H Zhu - Laboratory Investigation, 2018 - Elsevier
Human β-defensins contain an oncolytic motif that binds to tumor cell membranes and
mediate permeabilization, rapid induction of cytolysis, and apoptosis. Previous studies have …

Antimicrobial Peptides as Potential Therapy for Gastrointestinal Cancers: Opportunities and Challenges

L Ma, JP Dilger - Antimicrobial Peptides in Gastrointestinal Diseases, 2018 - Elsevier
Human cathelicidins and defensins have both pro-and antitumor effects in the
gastrointestinal (GI) tract. In vitro, AMPs promote tumor growth at low concentrations and …