Myelinating oligodendrocytes are essential for central nervous system (CNS) formation and
function. Their disruption is implicated in numerous neurodevelopmental, neuropsychiatric …

It is well established that brain structures and cognitive functions change across the life
span. A long-standing hypothesis called “age differentiation” additionally posits that the …

The objective of this study was to investigate whether the estimated myelin content of white
matter tracts is predictive of cognitive processing speed and whether such associations are …

Objective To assess brain structural connectivity in relation to cognitive abilities in healthy
ageing, and the mediating effects of white matter hyper‐intensity (WMH) volume. Methods …

Brain nerve fibers are insulated by myelin which is produced by oligodendrocytes. Defects in
myelination are increasingly recognized as a common pathology underlying …

Introduction The hippocampus plays an important role in cognitive abilities which often
decline with advancing age. Methods In a longitudinal study of community‐dwelling adults …

Understanding the precise relation between functional connectivity and structural (white
matter) connectivity and how these relationships account for cognitive changes in older …

Objectives: Subjective memory complaints (SMCs) are among the key concerns in the
elderly, but their role in detecting objective cognitive problems is unclear. The aim of this …

Background: Cognitive and biological markers have shown varying degrees of success in
identifying persons who will develop dementia. Objective: To evaluate different …

Little is known about white matter microstructure and its role in information processing
abilities of children treated for acute lymphoblastic leukemia (ALL) early posttreatment …