Early stage NSCLC—challenges to implementing ctDNA-based screening and MRD detection

C Abbosh, NJ Birkbak, C Swanton - Nature Reviews Clinical Oncology, 2018 - nature.com
Circulating tumour DNA (ctDNA) refers to the fraction of cell-free DNA in a patient's blood
that originates from a tumour. Advances in DNA sequencing technologies and our …

Development and validation of web-based nomograms to precisely predict conditional risk of site-specific recurrence for patients with completely resected non-small …

Y Zhang, D Zheng, J Xie, Y Li, Y Wang, C Li, J Xiang… - Chest, 2018 - Elsevier
Background There is currently no consensus regarding the optimal postoperative follow-up
strategy for patients with completely resected non-small cell lung cancer (NSCLC). We …

Cost-effectiveness analysis of stereotactic body radiotherapy and surgery for medically operable early stage non small cell lung cancer

A Paix, G Noel, PE Falcoz, P Levy - Radiotherapy and Oncology, 2018 - Elsevier
Background Projections estimate an increase of 50% of the incidence of lung cancer by
2030. Early-stage non-small cell lung cancer represented 19% of NSCLC cases diagnosed …

Standardization and optimization of intraoperative molecular imaging for identifying primary pulmonary adenocarcinomas

JD Predina, O Okusanya, A D. Newton, P Low… - Molecular Imaging and …, 2018 - Springer
Purpose Intraoperative molecular imaging (IMI) is an emerging technology used to locate
pulmonary adenocarcinomas and identify positive margins during surgery. Background …

[HTML][HTML] Current outcomes of postrecurrence survival in patients after resection of non-small cell lung cancer

T Mizuno, T Arimura, H Kuroda… - Journal of Thoracic …, 2018 - ncbi.nlm.nih.gov
Background Despite complete resection, patients with resectable non-small cell lung cancer
(NSCLC) sometimes experience recurrence in various sites, generally with an unfavorable …

[HTML][HTML] Editorial on “Long-term survival outcome after postoperative recurrence of non-small cell lung cancer: who is 'cured'from postoperative recurrence?”

J Pfannschmidt - Journal of Thoracic Disease, 2018 - ncbi.nlm.nih.gov
© Journal of Thoracic Disease. All rights reserved. J Thorac Dis 2018; 10 (2): 610-613 jtd.
amegroups. com risk of local and regional recurrence, with local recurrence rates between …

Prognostic factors for post-recurrence survival in patients with completely resected Stage III (N2) non-small-cell lung cancer

S Cho, S Yum, K Kim, S Jheon - European Journal of Cardio …, 2018 - academic.oup.com
OBJECTIVES The aim of this study was to investigate the prognostic factors for post-
recurrence survival (PRS) in patients with completely resected Stage III (N2) non-small-cell …

Bronchial stump recurrence after complete resection of lung cancer: effect of the distance between the tumor and bronchial resection margin

MZ Gunluoglu, CI Kocaturk, A Demir… - The Thoracic and …, 2018 - thieme-connect.com
Purpose The purpose of this study was to evaluate the following parameters after complete
resection in established lung cancer patients: the frequency of bronchial stump recurrence …

Linear Endobronchial Ultrasound: What's New?

T He, AC Mehta - Seminars in Respiratory and Critical Care …, 2018 - thieme-connect.com
Since its advent more than a decade ago, real-time linear endobronchial ultrasound (EBUS)
guided transbronchial needle aspiration has revolutionized the diagnosis and staging of …

Isolated brain metastases as the first relapse after the curative surgical resection in non–small-cell lung cancer patients with an EGFR mutation

S Sadoyama, A Sekine, H Satoh, T Iwasawa, T Kato… - Clinical Lung Cancer, 2018 - Elsevier
Introduction The aim of this study was to clarify the incidence and disease behavior of brain
metastases (BM) without extracranial disease (ie, isolated BM) as the first relapse after …