The podocytes within the glomeruli of the kidney maintain the filtration barrier by forming
interdigitating foot processes with intervening slit diaphragms, disruption in which results in …

Chronic kidney disease (CKD) represents the fastest growing pathology worldwide with a
prevalence of> 10% in many countries. In addition, kidney cancer represents 5% of all new …

Understanding epigenetic mechanisms is crucial to our comprehension of gene regulation
in development and disease. In the past decades, different studies have shown the role of …

The emerging field of transcriptional regulation of cell shape changes aims to address the
critical question of how gene expression programs produce a change in cell shape …

The human kidney has a complex structure and diverse interactions among its cells and cell
components, both during homeostasis and in its diseased states. To better understand the …

Eine der häufigsten Missbildungen der Harnwege ist die einfache Ektopie der Niere, bei der
das Organ im kleinen Becken liegt. Bei der etwas selteneren gekreuzten Ektopie liegt die …

Doğumsal böbrek ve idrar yolu anomalileri çocuklarda kronik böbrek hastalıklarının en sık
nedenidir. Doğumsal üriner sistem anomalilerinin (DÜSA) patogenezi net olarak …

Kidney diseases affect an increasing number of people worldwide, and there is a growing
demand to develop new treatments and increase the number of transplantable organs. New …

Diabetic nephropathy (DN) is the most prevalent and severe complication of diabetes,
affecting up to one-third of diabetics. Normally, it takes many years to develop DN since the …