Epigenetics and developmental origins of diabetes: correlation or causation?

A Bansal, RA Simmons - American Journal of Physiology …, 2018 - journals.physiology.org
The incidence of metabolic disorders like type 2 diabetes (T2D) and obesity continue to
increase. Although it is evident that the increasing incidence of diabetes confers a global …

Birth weight predicts aging trajectory: A hypothesis

AM Vaiserman - Mechanisms of ageing and development, 2018 - Elsevier
Increasing evidence suggests that risk for age-related disease and longevity can be
programmed early in life. In human populations, convincing evidence has been …

ExtraUterine Growth Restriction (EUGR) in preterm infants: Growth patterns, nutrition, and epigenetic markers. A pilot study

MG Tozzi, F Moscuzza, A Michelucci… - Frontiers in …, 2018 - frontiersin.org
Background/Aims: IntraUterine (IUGR) and ExtraUterine Growth Restriction (EUGR) may
induce reprogramming mechanisms, finalized to survive before and after birth. Nutritional …

The impact of nutritional interventions in pregnant women on DNA methylation patterns of the offspring: a systematic review

S Andraos, JV de Seymour… - Molecular nutrition & …, 2018 - Wiley Online Library
Epidemiological studies have consistently demonstrated that environmental exposures in
early life are associated with later‐life health status and disease susceptibility. Epigenetic …

Epigenetic modifications linked to T2D, the heritability gap, and potential therapeutic targets

M Szabó, B Máté, K Csép, T Benedek - Biochemical genetics, 2018 - Springer
With the pandemic of type 2 diabetes (T2D), there is an ever-increasing need to fully
understand the underlying mechanisms of the disease. Type 2 diabetes shows a high …

Emerging role of nutrition and the non-coding landscape in type 2 diabetes mellitus: A review of literature

M Matboli, A Shafei, M Ali, KM Kamal, M Noah, P Lewis… - Gene, 2018 - Elsevier
With the advent of recent advances in molecular techniques and whole genome
sequencing, we have come to know that the non-coding landscape (including non-coding …

Maternal low-quality protein diet exerts sex-specific effects on plasma amino acid profile and alters hepatic expression of methyltransferases in adult rat offspring

A Akyol, AK Cetin, A Gulec, H Dasgin… - … Origins of Health and …, 2018 - cambridge.org
Nutrition during pregnancy and lactation is a critical factor in the development of the
offspring. Both protein content and source in maternal diet affect neonatal health, but the …

[图书][B] Epigenetic Studies of Complex Human Disorders and Aging

RH Jeremian - 2018 - search.proquest.com
Aging is a major risk factor for nearly all human illnesses. Several of these have a strong
genetic and familial basis, but do not manifest until much later in life. Numerous studies have …

[HTML][HTML] Role of Fetal Programming and Epigenetic Regulation on the Development of Endocrine and Metabolic Alterations: Epigenetics and developmental origins of …

A Bansal, RA Simmons - American Journal of Physiology …, 2018 - ncbi.nlm.nih.gov
The incidence of metabolic disorders like type 2 diabetes (T2D) and obesity continue to
increase. Although it is evident that the increasing incidence of diabetes confers a global …