Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …

Abstract Purpose of Review Cerebral autoregulation (CA) is a mechanism that maintains
cerebral blood flow constant despite fluctuations in systemic arterial blood pressure. This …

Decreased cerebrovascular blood flow and function are associated with lower cognitive
functioning and increased risk of neurodegenerative diseases. Prolonged sitting impairs …

Out of hospital cardiac arrest is the leading cause of death in industrialized countries.
Recovery of hemodynamics does not necessarily lead to recovery of cerebral perfusion. The …

Sport-related concussion is known to affect a variety of brain functions. However, the impact
of this brain injury on cerebral autoregulation (CA) is poorly understood. Thus, the goal of …

New Findings What is the topic of this review? This review provides an up‐to‐date
assessment of the physiology involved with extreme static dry‐land breath holding in trained …

Ascent to high-altitude elicits compensatory physiological adaptations in order to improve
oxygenation throughout the body. The brain is particularly vulnerable to the hypoxemia of …

Blood velocity measured in the middle cerebral artery (MCAV) increases with finite kinetics
during moderate-intensity exercise, and the amplitude and dynamics of the response …

Cerebral blood flow (CBF) is regulated to secure brain O2 delivery while simultaneously
avoiding hyperperfusion; however, both requisites may conflict during sprint exercise. To …

In healthy individuals, cerebral blood flow (CBF) is regulated by different mechanisms that
maintain optimal blood supply to the brain, responding to changes in O2 demand …