Life expectancy is continuously increasing due to major progress in preventing, delaying or
curing various pathologies normally encountered in old age. However, both scientific and …

Objective To determine if chikungunya virus persists in synovial fluid after infection,
potentially acting as a causative mechanism of persistent arthritis. Methods We conducted a …

The physiology of the immune system involves morphologic and functional changes
occurring along ageing, with a decrease in immune response and an increase in …

Background Prognostic stratification of elderly patients with chronic obstructive pulmonary
disease (COPD) is difficult due to the wide inter-individual variability in the course of the …

During immunosenescence many proinflammatory markers such as cytokines and
chemokines are increased. This process called by Franceschi and colleagues as …

Caloric restriction increases lifespan and healthspan, and limits age-associated muscle
wasting. In this study, we investigate the impact of 30% caloric restriction (CR) in a murine …

Ageing is related to complex molecular, inflammatory and biochemical changes that affect
coronary pathology and often lead to coronary artery disease and cardiovascular events …

Background: The role of interleukin 6 in endometriosis has been extensively studied but
results were inconsistent. The purpose of this study was to determine the performance of …

This work had the purpose of comparing some renal parameters of Wistar rats raised in
small litters either freely-fed (G3L) or subjected to 30% caloric restriction (G3R) with those of …

Ageing is a major socioeconomic concern and a risk factor in most diseases. As such, a
better understanding of the ageing process could provide major insights into many disease …