Applications of Raman spectroscopy in cancer diagnosis

GW Auner, SK Koya, C Huang, B Broadbent… - Cancer and Metastasis …, 2018 - Springer
Novel approaches toward understanding the evolution of disease can lead to the discovery
of biomarkers that will enable better management of disease progression and improve …

Circulating tumor cell isolation, culture, and downstream molecular analysis

S Sharma, R Zhuang, M Long, M Pavlovic, Y Kang… - Biotechnology …, 2018 - Elsevier
Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a
promising prognostic significance in cancer detection. Performing functional and molecular …

Platelet–leukocyte hybrid membrane‐coated immunomagnetic beads for highly efficient and highly specific isolation of circulating tumor cells

L Rao, QF Meng, Q Huang, Z Wang… - Advanced Functional …, 2018 - Wiley Online Library
Biomimetic cell‐membrane‐camouflaged nanoparticles with desirable features have been
widely used for various biomedical applications. However, the current research focuses on …

Size-based separation methods of circulating tumor cells

SJ Hao, Y Wan, YQ Xia, X Zou, SY Zheng - Advanced drug delivery reviews, 2018 - Elsevier
Circulating tumor cells (CTCs) originate from the primary tumor mass and enter into the
peripheral bloodstream. Compared to other “liquid biopsy” portfolios such as exosome …

Genomic and functional fidelity of small cell lung cancer patient-derived xenografts

BJ Drapkin, J George, CL Christensen… - Cancer discovery, 2018 - AACR
Small cell lung cancer (SCLC) patient-derived xenografts (PDX) can be generated from
biopsies or circulating tumor cells (CTC), though scarcity of tissue and low efficiency of tumor …

Engineering carbon quantum dots for photomediated theranostics

M Hassan, VG Gomes, A Dehghani, SM Ardekani - Nano Research, 2018 - Springer
Carbon quantum dots (CQDs) have emerged as potential alternatives to classical metal-
based semiconductor quantum dots (QDs) due to the abundance of their precursors, their …

The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

MØ Agerbæk, SR Bang-Christensen, MH Yang… - Nature …, 2018 - nature.com
Isolation of metastatic circulating tumor cells (CTCs) from cancer patients is of high value for
disease monitoring and molecular characterization. Despite the development of many new …

Targeting and isolation of cancer cells using micro/nanomotors

W Gao, BEF de Ávila, L Zhang, J Wang - Advanced Drug Delivery Reviews, 2018 - Elsevier
Micro/nanomotors distinguish themselves with in situ energy conversion capability for
autonomous movement, a feature that confers remarkable potential to improve cancer …

The prognostic role of circulating tumor cells (CTCs) in lung cancer

J Kapeleris, A Kulasinghe, ME Warkiani, I Vela… - Frontiers in …, 2018 - frontiersin.org
Lung cancer affects over 1. 8 million people worldwide and is the leading cause of cancer
related mortality globally. Currently, diagnosis of lung cancer involves a combination of …

Cancer diagnosis using a liquid biopsy: challenges and expectations

F Castro-Giner, S Gkountela, C Donato, I Alborelli… - Diagnostics, 2018 - mdpi.com
The field of cancer diagnostics has recently been impacted by new and exciting
developments in the area of liquid biopsy. A liquid biopsy is a minimally invasive alternative …