[PDF][PDF] Once-a-week versus once-every-3-weeks cisplatin chemoradiation for locally advanced head and neck cancer: a phase III randomized noninferiority trial

V Noronha, A Joshi, VM Patil, J Agarwal… - Journal of Clinical …, 2018 - academia.edu
Purpose Chemoradiation with cisplatin 100 mg/m2 given once every 3 weeks is the
standard of care in locally advanced head and neck squamous cell cancer (LAHNSCC) …

Locally advanced squamous cell carcinoma of the head and neck: A systematic review and Bayesian network meta-analysis of the currently available treatment …

O Iocca, A Farcomeni, A Di Rocco, P Di Maio… - Oral oncology, 2018 - Elsevier
Background There are still many unresolved questions in the management of locally
advanced Head and Neck Cancer (HNC). Many chemotherapeutic drugs and radiotherapy …

Management of advanced hypopharyngeal carcinoma: systematic review of survival following surgical and non-surgical treatments

A Habib - The Journal of Laryngology & Otology, 2018 - cambridge.org
Background: Advanced hypopharyngeal carcinoma has a dismal prognosis. The optimal
treatment for these patients remains under debate. This systematic review aimed to compare …

Iridium nanocrystals encapsulated liposomes as near-infrared light controllable nanozymes for enhanced cancer radiotherapy

L Feng, Z Dong, C Liang, M Chen, D Tao, L Cheng… - Biomaterials, 2018 - Elsevier
Owing to the existence of severe tumor hypoxia and limited X-ray absorption of solid tumors,
the therapeutic efficacy of radiotherapy is far from satisfactory. Herein, ultrasmall iridium …

Refining patient selection for reirradiation of head and neck squamous carcinoma in the IMRT era: a multi-institution cohort study by the MIRI collaborative

MC Ward, N Riaz, JJ Caudell, NE Dunlap… - International Journal of …, 2018 - Elsevier
Purpose The therapeutic ratio of reirradiation for recurrent or second primary (RSP)
squamous carcinoma of the head and neck may be improved in the intensity modulated …

Oropharyngeal cancer

CH Chapman, SS Yom - Handbook of Evidence-Based Radiation …, 2018 - Springer
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[HTML][HTML] Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma

SMF Jamieson, P Tsai, MK Kondratyev, P Budhani… - JCI insight, 2018 - ncbi.nlm.nih.gov
Abstract Evofosfamide (TH-302) is a clinical-stage hypoxia-activated prodrug of a DNA-
crosslinking nitrogen mustard that has potential utility for human papillomavirus (HPV) …

Treatment deintensification in human papillomavirus‐positive oropharynx cancer: outcomes from the National Cancer Data Base

S Cheraghlou, PK Yu, MD Otremba, HS Park… - Cancer, 2018 - Wiley Online Library
BACKGROUND The growing epidemic of human papillomavirus‐positive (HPV+)
oropharyngeal cancer and the favorable prognosis of this disease etiology have led to a call …

De‐intensified adjuvant (chemo) radiotherapy versus standard adjuvant chemoradiotherapy post transoral minimally invasive surgery for resectable HPV‐positive …

J Howard, RC Dwivedi, L Masterson… - Cochrane Database …, 2018 - cochranelibrary.com
Background More than 400,000 cases of oropharyngeal squamous cell cancer (OPSCC) are
diagnosed every year worldwide and this is rising. Much of the increase has been attributed …

Retrospective analysis of cisplatin nephrotoxicity in patients with head and neck cancer receiving outpatient treatment with concurrent high-dose cisplatin and …

J Faig, M Haughton, RC Taylor… - American journal of …, 2018 - journals.lww.com
Objectives: Cisplatin remains the pivotal chemotherapy in squamous cell carcinoma of the
head and neck (SCCHN), with nephrotoxicity considered the dose-limiting toxicity. The …