Medicinal Chemistry of A2B Adenosine Receptors

CE Müller, Y Baqi, S Hinz, V Namasivayam - The adenosine receptors, 2018 - Springer
Abstract A 2B adenosine receptors (A 2B ARs) are in the focus of interest as drug targets in
(immuno) oncology since antagonists show anti-proliferative, anti-angiogenic, anti …

7-Transmembrane Helical (7TMH) Proteins: Pseudo-Symmetry and Conformational Plasticity

P Youkharibache, A Tran, R Abrol - 2018 - europepmc.org
Membrane proteins sharing 7 transmembrane helices (7-TMH) dominate the polytopic TMH
proteome. They cannot be grouped under a monolithic fold or superfold, however, a parallel …

Pseudo-Symmetry and Conformational Plasticity in 7 Transmembrane Helix (7TMH) Proteins: Intragenic Duplication and Assembly of 3TMH or 4TMH Protodomains …

P Youkharibache, A Tran, R Abrol - bioRxiv, 2018 - biorxiv.org
Transmembrane-Helix (7TMH) proteins cannot be grouped under a monolithic fold or
superfold. A parallel structure-based analysis of pseudo-symmetric membrane domains …