Chronic innate immune signaling in hematopoietic cells is widely described in
myelodysplastic syndromes (MDS), and innate immune pathway activation, predominantly …

Anemia is characteristic of myelodysplastic syndromes (MDS). The mechanisms of anemia
in MDS are unclear. Using a mouse genetic approach, here we show that dual deficiency of …

KDM6B is an epigenetic regulator that mediates transcriptional activation during
differentiation, including in bone marrow (BM) hematopoietic stem and progenitor cells …

Myelodysplastic syndromes (MDS) are a group of clonal hematologic malignancies
characterized by cytopenia, ineffective hematopoiesis, and an increased risk of progression …

Миелодиспластические синдромы (МДС)–гетерогенная группа клональных
заболеваний системы кроветворения, характеризуемых цитопениями, признаками …

Myelodysplastic syndromes (MDS) are heterogeneous group of clonal hematological
neoplasms characterized by cytopenias, sighs of dysplasia and high risk of transformation in …

Despite recent advances in cancer therapy, most hematological malignancies remain
incurable. Mantle cell lymphoma (MCL), a B-cell non-Hodkin's lymphoma, and the …

The aim of this study was to assess the association between CD14-159 genotypes and
DLBCL characteristics, clinical course and outcome, respectively. The study included 114 …

The platelet and megakaryocyte cytoskeletons are essential for formation and function of
these cells. A dynamic, properly organised tubulin and actin cytoskeleton is critical for the …