Gene maps, or annotations, enable us to navigate the functional landscape of our genome.
They are a resource upon which virtually all studies depend, from single-gene to genome …

INTRODUCTION Wheat (Triticum aestivum L.) is the most widely cultivated crop on Earth,
contributing about a fifth of the total calories consumed by humans. Consequently, wheat …

Patient-derived organoids (PDOs) have recently emerged as robust preclinical models;
however, their potential to predict clinical outcomes in patients has remained unclear. We …

Ferns are the closest sister group to all seed plants, yet little is known about their genomes
other than that they are generally colossal. Here, we report on the genomes of Azolla …

Newborn microglia rapidly replenish the whole brain after selective elimination of most
microglia (> 99%) in adult mice. Previous studies reported that repopulated microglia were …

Sequencing the RNA in a biological sample can unlock a wealth of information, including
the identity of bacteria and viruses, the nuances of alternative splicing or the transcriptional …

Combining whole exome sequencing, transcriptome profiling, and T cell repertoire analysis,
we investigate the spatial features of surgically-removed biopsies from multiple loci in tumor …

The human genome contains thousands of long non-coding RNAs, but specific biological
functions and biochemical mechanisms have been discovered for only about a dozen,,,,–. A …

We assembled the sequences from deep RNA sequencing experiments by the Genotype-
Tissue Expression (GTEx) project, to create a new catalog of human genes and transcripts …

Background & Aims It is not clear how the complex interactions between diet and the
intestinal microbiota affect development of mucosal inflammation or inflammatory bowel …