Omega-3 fatty acids and non-alcoholic fatty liver disease: Evidence of efficacy and mechanism of action
E Scorletti, CD Byrne - Molecular aspects of medicine, 2018 - Elsevier
For many years it has been known that high doses of long chain omega-3 fatty acids are
beneficial in the treatment of hypertriglyceridaemia. Over the last three decades, there has …
beneficial in the treatment of hypertriglyceridaemia. Over the last three decades, there has …
Omega-3 polyunsaturated fatty acids as a treatment strategy for nonalcoholic fatty liver disease
Obese and type 2 diabetic (T2DM) patients have a high prevalence of nonalcoholic fatty liver
disease (NAFLD). NAFLD is a continuum of chronic liver diseases ranging from benign …
disease (NAFLD). NAFLD is a continuum of chronic liver diseases ranging from benign …
Is palmitoleic acid a plausible nonpharmacological strategy to prevent or control chronic metabolic and inflammatory disorders?
CO de Souza, GK Vannice… - Molecular Nutrition & …, 2018 - Wiley Online Library
Although dietary fatty acids can modulate metabolic and immune responses, the effects of
palmitoleic acid (16: 1n‐7) remain unclear. Since this monounsaturated fatty acid is …
palmitoleic acid (16: 1n‐7) remain unclear. Since this monounsaturated fatty acid is …
Metaflammation: tissue-specific alterations of the NLRP3 inflammasome platform in metabolic syndrome
R Mastrocola, M Aragno, G Alloatti… - Current Medicinal …, 2018 - ingentaconnect.com
In the last decades, the extension of life expectancy and the increased consumption of foods
rich in saturated fats and added sugars have exposed the general population to emerging …
rich in saturated fats and added sugars have exposed the general population to emerging …
ELOVL4-mediated production of very long-chain ceramides stabilizes tight junctions and prevents diabetes-induced retinal vascular permeability
NM Kady, X Liu, TA Lydic, MH Syed, S Navitskaya… - Diabetes, 2018 - Am Diabetes Assoc
Tight junctions (TJs) involve close apposition of transmembrane proteins between cells.
Although TJ proteins have been studied in detail, the role of lipids is largely unknown. We …
Although TJ proteins have been studied in detail, the role of lipids is largely unknown. We …
Dominant ELOVL1 mutation causes neurological disorder with ichthyotic keratoderma, spasticity, hypomyelination and dysmorphic features
A Kutkowska-Kaźmierczak, M Rydzanicz… - Journal of medical …, 2018 - jmg.bmj.com
Background Ichthyosis and neurological involvement occur in relatively few known
Mendelian disorders caused by mutations in genes relevant both for epidermis and neural …
Mendelian disorders caused by mutations in genes relevant both for epidermis and neural …
A High‐Fat Diet Rich in Saturated and Mono‐Unsaturated Fatty Acids Induces Disturbance of Thyroid Lipid Profile and Hypothyroxinemia in Male Rats
Scope Increasing evidence has shown that the disturbance of lipid metabolism might make
a possible contribution to the pathogenesis of organ dysfunction, including thyroid, yet it is …
a possible contribution to the pathogenesis of organ dysfunction, including thyroid, yet it is …
Long-term exposure to high-sucrose diet down-regulates hepatic endoplasmic reticulum-stress adaptive pathways and potentiates de novo lipogenesis in weaned …
Childhood consumption of added sugars, such as sucrose, has been associated to
increased risk of metabolic syndrome (MetS) and nonalcoholic fatty liver disease (NAFLD) …
increased risk of metabolic syndrome (MetS) and nonalcoholic fatty liver disease (NAFLD) …
[HTML][HTML] Fatty acid elongase 5 (ELOVL5) alters the synthesis of long-chain unsaturated fatty acids in goat mammary epithelial cells
HB Shi, Y Du, CH Zhang, C Sun, YL He, YH Wu… - Journal of dairy …, 2018 - Elsevier
Increased production of long-chain unsaturated fatty acids (LCUFA) can have a positive
effect on the nutritional value of ruminant milk for human consumption. In nonruminant …
effect on the nutritional value of ruminant milk for human consumption. In nonruminant …
Effect of dietary polyunsaturated fatty acid and antioxidant supplementation on the transcriptional level of genes involved in lipid and energy metabolism in swine
Porcine fat traits depend mostly on the interaction between nutritional and genetic factors.
However, the pathways and biological processes influenced by this interaction are still …
However, the pathways and biological processes influenced by this interaction are still …