Overcrowding conditions and temperatures shifts regularly manifest in large-scale infections
of farmed fish, resulting in economic losses for the global aquaculture industries. Increased …

The zebrafish has become a widely accepted model host for studies of infectious disease,
including fungal infections. The species is genetically tractable, and the larvae are …

Spinal cord injury leads to a massive response of innate immune cells in non-regenerating
mammals, but also in successfully regenerating zebrafish. However, the role of the immune …

Major molecular mechanisms that underpin the toxicity of nanoparticles (NPs) are the
formation of reactive oxygen species and the induction of inflammation. The latter is …

Similar to higher vertebrates, the immune system of fish is composed of two major
components, innate (non-specific) and adaptive (specific) immune responses. However, the …

Tumour angiogenesis has long been a focus of anti-cancer therapy; however, anti-
angiogenic cancer treatment strategies have had limited clinical success. Tumour …

In the present review we discuss two interrelated events—axonal damage and repair—
known to occur after spinal cord injury (SCI) in the zebrafish. Adult zebrafish are capable of …

The cellular events that contribute to tissue healing of non-sterile wounds to the skin and
ischaemic injury to internal organs such as the heart share remarkable similarities despite …

The mammalian central nervous system is not able to regenerate neurons lost upon injury.
In contrast, anamniote vertebrates show a remarkable regenerative capacity and are able to …

The pancreatic islet, a cellular community harboring the insulin-producing beta-cells, is
known to undergo age-related alterations. However, only a handful of signals associated …