Systemic sclerosis (SSc) is a severe auto-immune disease, characterized by vasculopathy
and fibrosis of connective tissues. SSc has a high morbidity and mortality and unfortunately …

A proportion of patients with interstitial lung diseases (ILDs) are at risk of developing a
progressive-fibrosing phenotype, which is associated with a deterioration in lung function …

Rationale: FVC percent predicted (FVC%) is the primary outcome measure in clinical trials of
systemic sclerosis interstitial lung disease. For interpretation of change in the FVC% over …

Systemic sclerosis (SSc) is associated with high mortality owing to internal organ
complications, and lung disease is the leading cause of SSc-associated death. The most …

Systemic sclerosis is a rare acquired systemic disease characterised by a complex
pathogenesis and multi organ involvement. Every year the scientific world contributes to …

Introduction Despite extensive multidisciplinary team (MDT) assessment, some patients
have interstitial lung disease (ILD) that is considered unclassifiable (uILD), for which there …

Background and objective Interstitial lung disease (ILD) is a common pulmonary
manifestation of systemic sclerosis (SSc). It is unknown whether radiographic fibrosis score …

New treatment paradigms for connective tissue disease-associ... : Current Opinion in Pulmonary
Medicine New treatment paradigms for connective tissue disease-associated interstitial lung …

Objectives: We retrospectively investigated efficacy and safety of combination therapy with
prednisolone (PSL) and tacrolimus (TAC) for progressive interstitial pneumonitis with …

Systemic sclerosis is a connective tissue disease characterized by progressive skin
thickening and a wide spectrum of internal organ involvement. Pathogenesis includes …