Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease
S Hunter, C Brayne - Molecular psychiatry, 2018 - nature.com
Many models of disease progression in Alzheimer's disease (AD) have been proposed to
help guide experimental design and aid the interpretation of results. Models focussing on …
help guide experimental design and aid the interpretation of results. Models focussing on …
[HTML][HTML] Differences in synaptic dysfunction between rTg4510 and APP/PS1 mouse models of Alzheimer's disease
S Gelman, J Palma, G Tombaugh… - Journal of Alzheimer's …, 2018 - content.iospress.com
Genetically modified mice have provided insights into the progression and pathology of
Alzheimer's disease (AD). Here, we have examined two mouse models of AD: the rTg4510 …
Alzheimer's disease (AD). Here, we have examined two mouse models of AD: the rTg4510 …
[HTML][HTML] Genetic screening in early-onset dementia patients with unclear phenotype: relevance for clinical diagnosis
In a prospective study of dementia in Flanders (Belgium), we observed a substantial fraction
of early-onset dementia patients who did not fulfill the criteria for a specific dementia …
of early-onset dementia patients who did not fulfill the criteria for a specific dementia …
[HTML][HTML] Translational research in Alzheimer's and Prion diseases
Translational neuroscience integrates the knowledge derived by basic neuroscience with
the development of new diagnostic and therapeutic tools that may be applied to clinical …
the development of new diagnostic and therapeutic tools that may be applied to clinical …
Natural products against neurodegenerative diseases: effects in the model organism Caenorhabditis elegans
P Link - 2018 - archiv.ub.uni-heidelberg.de
Neurodegenerative diseases are a growing burden in the modern ageing societies.
Especially Alzheimer's disease (AD)—the most common form of dementia—has gained lot of …
Especially Alzheimer's disease (AD)—the most common form of dementia—has gained lot of …
[HTML][HTML] 中药免疫治疗阿尔茨海默病的研究进展
王莎莎， 张钊， 张欣， 龙倩， 贺文彬， 陈乃宏 - 药学学报, 2018 - html.rhhz.net
阿尔茨海默病(Alzheimer's disease, AD) 是一种常见的神经退行性疾病, 临床以进行性认知功能
障碍为核心症状, 目前尚无理想的治疗策略. 随着免疫学在中枢神经系统研究的深入 …
障碍为核心症状, 目前尚无理想的治疗策略. 随着免疫学在中枢神经系统研究的深入 …
Aβ conformer selective anti-Aβ globulomer monoclonal antibodies
S Barghorn, H Hillen, AR Striebinger… - US Patent …, 2018 - Google Patents
The subject invention relates to monoclonal antibodies that may be used in the treatment
and diagnosis of Alzheimer's Disease. In particular, the present invention relates to …
and diagnosis of Alzheimer's Disease. In particular, the present invention relates to …
Amyloid-beta binding proteins
S Barghorn, H Hillen, A Striebinger, S Giaisi… - US Patent …, 2018 - Google Patents
2016-06-29 Assigned to AbbVie Deutschland GmbH & Co. KG reassignment AbbVie
Deutschland GmbH & Co. KG ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
Deutschland GmbH & Co. KG ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
[引用][C] The Correlation between Genotype and Phenotype of Alzheimer's Disease. A Retrospective Analysis in the Tajiri Project
HL Li, B Jiang, ZY Wu - J Alzheimers Dis Parkinsonism, 2018