Evidence from the literature keeps highlighting the impact of mutualistic bacterial
communities of the gut microbiota on human health. The gut microbita is a complex …

Accumulation of dysfunctional white adipose tissues increases risks for cardiometabolic
diseases in obesity. In addition to white, brown or brite adipose tissues are also present in …

Increasing brown adipose tissue (BAT) thermogenesis in mice and humans improves
metabolic health and understanding BAT function is of interest for novel approaches to …

In the 1980s, mouse nuclear transplantation experiments revealed that both male and
female parental genomes are required for successful development to term (;). This non …

Background Exposure to endocrine-disrupting chemicals can alter normal physiology and
increase susceptibility to non-communicable diseases like obesity. Especially the prenatal …

Background Pregnancy is a time of high risk for excessive weight gain, leading to health-
related consequences for mothers and offspring. Theory-based obesity interventions that …

Barrington et al. examined the effect of four human diets (American, Mediterranean,
Japanese, and Maasai/ketogenic) on metabolic health across four mouse... The incidence of …

Type 2 diabetes is an age-and-obesity associated disease driven by impairments in glucose
homeostasis that ultimately result in defective insulin secretion from pancreatic β-cells. To …

Adipogenesis is a tightly regulated cellular process and is closely associated with obesity
and its associated metabolic disorders, such as diabetes. Multiple transcription factors and …

Previous studies with gene-deficient mice (ADAMTS5-P) revealed that ADAMTS5 (A
Disintegrin And Metalloproteinase with Thrombospondin type 1 motifs, member 5) plays a …